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Referencia número: HY-161309

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RUPB-61

RUPB-61 is a potent Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) inhibitor with an IC₅₀ value of 13 nM. RUPB-61 shows antiparasitic activity.

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No. CAS: 3032827-64-5
Fòrmula: C₂₂H₂₄FN₃
Peso molecular:349.44

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

RUPB-61 Chemical Structure

No. CAS: 3032827-64-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Descripciòn
- IC₅₀ & Target
Chemical Information
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Actividad biológica

Descripciòn

RUPB-61 is a potent Plasmodium falciparum cGMP-dependent protein kinase (PfPKG) inhibitor with an IC₅₀ value of 13 nM. RUPB-61 shows antiparasitic activity^[1].

IC₅₀ & Target

IC₅₀:13 nM (PfPKG)^[1]

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Chemical Information

No. CAS 3032827-64-5
Peso molecular 349.44
Fòrmula C₂₂H₂₄FN₃
SMILES

FC(C=C1)=CC=C1C(NC([C@@H]2[C@H](C)CN(C)CC2)=C3)=C3C4=CC=NC=C4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (281 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Gilleran JA, et al. Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials. J Med Chem. 2024 Feb 19. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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RUPB-61

Ver todos los productos específicos de isoformas Parasite

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

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RUPB-61 Related Classifications

HY-161309 Related Classifications