QL-IX-55
QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1223002-54-7
- Fòrmula: C24H14F4N4O
- Peso molecular:450.39
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PC-3 | EC50 |
250 nM
Compound: 11
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Inhibition of PI3Kalpha in human PC3 cells expressing Akt1 S473D mutant assessed as phosphorylation of Akt Thr308 by immunoblotting
Inhibition of PI3Kalpha in human PC3 cells expressing Akt1 S473D mutant assessed as phosphorylation of Akt Thr308 by immunoblotting
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[PMID: 21322566] |
Chemical Information
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No. CAS 1223002-54-7
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Peso molecular 450.39
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Fòrmula C24H14F4N4O
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SMILES
NC1=NC=C(C2=CC=C(N=CC(C=C3)=C4N(C5=CC(C(F)(F)F)=C(F)C=C5)C3=O)C4=C2)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
QL-IX-55 Related Classifications
HY-15281 Related Classifications
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