SC 34301
SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice.
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- No. CAS: 81026-63-3
- Fòrmula: C22H36O5
- Peso molecular:380.52
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:BALB/c mice (E. coli, burned)[1]
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Dosage:200 µg/kg
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Administration:P.o.; once a day for three days
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Result:Significantly reduced the degree of bacterial translocation as measured by blood dpm counts, improved survival rate to 60% in burned mice.
Chemical Information
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No. CAS 81026-63-3
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Peso molecular 380.52
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Fòrmula C22H36O5
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SMILES
CCCCC(C)(O)C/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CC/C=C\CCC(OC)=O
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Synonyms
Enisoprost
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Pollak R, et al. A trial of the prostaglandin E1 analogue, enisoprost, to reverse chronic cyclosporine-associated renal dysfunction. Am J Kidney Dis. 1992 Oct;20(4):336-41. [Content Brief]
[2]. Fukushima R, et al. The degree of bacterial translocation is a determinant factor for mortality after burn injury and is improved by prostaglandin analogs. Ann Surg. 1992 Oct;216(4):438-44; discussion 444-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)