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Referencia número: HY-120053

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SC-53606

SC-53606 is a potent and selective 5-HT₄ receptor antagonist, with a pA2 value of 8.13. SC-53606 acts as an antagonist of 5-HT₄ receptor-mediated relaxation of Carbachol (HY-B1208)-induced contractions.

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No. CAS: 151898-33-8
Fòrmula: C₁₆H₁₉ClN₄O
Peso molecular:318.80

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

SC-53606 Chemical Structure

No. CAS: 151898-33-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

IC₅₀ & Target^[1]^[2]

5-HT₄ Receptor

Ver todos los productos específicos de isoformas 5-HT Receptor :

Chemical Information

No. CAS 151898-33-8
Peso molecular 318.80
Fòrmula C₁₆H₁₉ClN₄O
SMILES

O=C(NC[C@H]1[C@@]2(CCCN2CC1)[H])C3=CC(Cl)=CN4C3=NC=C4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Yang DC, et al. SC-53606, a potent and selective antagonist of 5-hydroxytryptamine4 receptors in isolated rat esophageal tunica muscularis mucosae. J Pharmacol Exp Ther. 1993 Sep;266(3):1339-47. [Content Brief]

[2]. Becker D P, et al. Design and synthesis of agonists and antagonists of the serotonin 5-HT4 receptor subtype. Pharmacochemistry Library. Elsevier, 1996, 24: 99-120.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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SC-53606

Ver todos los productos específicos de isoformas 5-HT Receptor

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

SC-53606 Related Classifications

HY-120053 Related Classifications