Surbinsertib
Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research.
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- No. CAS: 3038330-83-2
- Fòrmula: C30H40N8O2S
- Peso molecular:576.76
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
In Vitro
Both Wee1 and Myt1 are CDK-inhibitory kinases. Wee1 primarily phosphorylates CDK1‑Tyr15, while Myt1 phosphorylates both CDK1‑Tyr15 and Thr14. The two kinases act synergistically to inhibit CDK1 activity and regulate the G2/M cell cycle transition.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3038330-83-2
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Peso molecular 576.76
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Fòrmula C30H40N8O2S
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SMILES
C[C@]12[C@](CC(C)(OC2)C)([H])N(C3=CC=CC(N=S(C)(C)=O)=N3)C4=NC(NC5=CC=C(N6CCN(CC6)C)C=C5)=NC=C41
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Synonyms
SGR-3515
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)