Tipranavir-d5
Tipranavir-d5 (PNU-140690-d5) is the deuterium labeled Tipranavir (HY-15148). Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC50s of 66-410 nM. Tipranavir inhibits SARS-CoV-2 3CLpro activity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1126619-17-7
- Fòrmula: C31H28D5F3N2O5S
- Peso molecular:607.70
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 1126619-17-7
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Unlabeled Cas 174484-41-4
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Peso molecular 607.70
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Fòrmula C31H28D5F3N2O5S
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SMILES
O=S(C1=NC=C(C(F)(F)F)C=C1)(NC2=CC=CC([C@H](C3=C(O)C[C@@](CCC)(CCC4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])OC3=O)CC)=C2)=O
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Synonyms
PNU-140690-d5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)