Tn antigen
Tn Antigen (Tn Epitope) (Compound 1) is a Trypanosoma cruzi trans-sialidase (TcTS) inhibitor with inhibition rate of 57% at 1 mM. Tn Antigen shows anti-trypanosomal activity with an IC50 of >0.5 mM. Tn Antigen can be used for the research of Chagas’ disease.
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- No. CAS: 67262-86-6
- Fòrmula: C11H20N2O8
- Peso molecular:308.29
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LLC-MK2 | IC50 |
>0.5 mM
Compound: 1
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Antitrypanosomal activity against trypomastigote form of Trypanosoma cruzi Tulahuen expressing beta galactosidase infected in rhesus monkey LLC-MK2 cells assessed as inhibition of parasite viability treated at 24 hrs post-infection measured after 4 days b
Antitrypanosomal activity against trypomastigote form of Trypanosoma cruzi Tulahuen expressing beta galactosidase infected in rhesus monkey LLC-MK2 cells assessed as inhibition of parasite viability treated at 24 hrs post-infection measured after 4 days b
|
[PMID: 23415086] |
| LLC-MK2 | IC50 |
0.5 mM
Compound: 1
|
Antitrypanosomal activity against trypomastigote form of Trypanosoma cruzi Tulahuen expressing beta galactosidase infected in rhesus monkey LLC-MK2 cells assessed as inhibition of parasite viability treated at 24 hrs post-infection measured after 4 days b
Antitrypanosomal activity against trypomastigote form of Trypanosoma cruzi Tulahuen expressing beta galactosidase infected in rhesus monkey LLC-MK2 cells assessed as inhibition of parasite viability treated at 24 hrs post-infection measured after 4 days b
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[PMID: 23415086] |
Chemical Information
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No. CAS 67262-86-6
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Peso molecular 308.29
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Fòrmula C11H20N2O8
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SMILES
O[C@@H]([C@H]1O)[C@@H](NC(C)=O)[C@@H](OC[C@H](N)C(O)=O)O[C@@H]1CO
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Synonyms
GalNAcα-O-Ser
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tn antigen Related Classifications
HY-W040126 Related Classifications
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