WSD0628
Based on 1 Customer Validation
WSD0628 is a brain penetrant and potent ATM inhibitor with profound radiosensitizing effect.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.43%
- No. CAS: 2765448-96-0
- Fòrmula: C23H23F2N5O2
- Peso molecular:439.46
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Almacenamiento:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Actividad biológica
WSD0628 significantly increased the radiosensitivity of U251 cells in clonogenic survival assays (0 nM vs. 30 nM at 5Gy, p<0.01)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 2765448-96-0
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Appearance Solid
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Peso molecular 439.46
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Fòrmula C23H23F2N5O2
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Color Off-white to light yellow
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SMILES
CN(C(N1[C@H]2C(F)(F)CN(C)CC2)=O)C3=C1C4=CC(C5=CN=C(OC)C=C5)=CC=C4N=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)