GDC-0152-acetamide
GDC-0152-acetamide is a pan-inhibitor of apoptosis protein (IAP) antagonist. GDC-0152-acetamide induces cIAP1/2 autoubiquitination and degradation, activating the non-canonical NF-κB pathway to promote TNF-α secretion and tumor cell apoptosis. GDC-0152-acetamide is promising for research of ERα-positive breast cancer.
For research use only. We do not sell to patients.
- Formula: C28H38N6O4S
- Molecular Weight:554.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 554.70
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Formula C28H38N6O4S
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SMILES
CC(NC1=NC(C2=CC=CC=C2)=C(NC([C@@H]3CCCN3C([C@@H](NC([C@H](C)NC)=O)C4CCCCC4)=O)=O)S1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)