1 Result for "

146540

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "146540" in MCE Product Catalog:

Art. -Nr.: HY-146540
CAS. Nr.: 2233543-49-0
Forschungsgebiete:  

Cancer

GEM-5 is a gemcitabine-based conjugate containing a HIF-1α inhibitor (YC-1) (IC50=30 nM). GEM-5 can significantly down-regulate the expression of HIF-1α and up-regulate the expression of tumor suppressor p53. GEM-5 induces the apoptosis of A2780 cells and inhibits tumor growth .
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