Il11 - interleukin 11 Gene

Also Known as IL-11

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16156

Summary

Enables cytokine activity and interleukin-11 receptor binding activity. Acts upstream of or within positive regulation of cell population proliferation. Located in cytoplasm. Orthologous to human IL11 (interleukin 11). [provided by Alliance of Genome Resources, Apr 2022]

Il11 Products (5)

mRNA Protein Name
NM_001290423.2 NP_001277352.1 interleukin-11 isoform 2
NM_001412482.1 NP_001399411.1 interleukin-11 isoform 2
NM_001412483.1 NP_001399412.1 interleukin-11 isoform 2
NM_001412484.1 NP_001399413.1 interleukin-11 isoform 2
NM_008350.5 NP_032376.1 interleukin-11 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IDA
IDA: Inferred from direct assay
7957045 MGI
enables interleukin-11 receptor binding IPI
IPI: Inferred from physical interaction
7957045 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of cell population proliferation IDA
IDA: Inferred from direct assay
7957045 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
7957045 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11737071 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-11

Recombinant Il11 Proteins

Cat. No. Product Name Accession Purity
HY-P7075A IL-11 Protein, Mouse (HEK293) P47873 (G23-L199) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P70356 IL-11 Protein, Mouse (HEK293, Fc) P47873 (P22-L199) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73155 IL-11 Protein, Mouse P47873/NP_032376.1 (P22-L199) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700189AF Animal-Free IL-11 Protein, Mouse (His) P47873 (P22-L199) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991487 LASN01 98.96% Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11623 4L2-P13D 91.58% Unkown
HY-RS16646 Il11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06675 IL11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06676 IL11RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174643 Human IL11RA mRNA / Unkown
HY-174644 Human IL11 mRNA / Unkown
HY-N14323 Madindoline A Inhibitor / Unkown
HY-RS23080 Il11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991218 Anti-IL11 Antibody (X203) 98.53% Unkown
HY-P991488 BI-765423 Inhibitor 95.52% Unkown
HY-P991219 Anti-IL11RA Antibody (X209) Inhibitor 97.75% Unkown
HY-P991736 Anti-IL11 Antibody (X203, Mouse IgG) 99.45% Unkown
HY-P991489 ENx-108A Inhibitor / Unkown
HY-P992039 Anti-IL-11 Antibody Inhibitor / Unkown
HY-P992235 Anti-IL11RA Antibody (Hu16E12) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il11 NCBI NCBI:3589