Il9 - interleukin 9 Gene

Also Known as P40; Il-9

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16198

Summary

Enables cytokine activity. Involved in positive regulation of interleukin-5 production. Acts upstream of or within several processes, including B cell activation; regulation of cellular protein metabolic process; and regulation of receptor signaling pathway via JAK-STAT. Located in extracellular space. Is expressed in gut; liver; thymus; and thymus primordium. Human ortholog(s) of this gene implicated in asthma and respiratory syncytial virus infectious disease. Orthologous to human IL9 (interleukin 9). [provided by Alliance of Genome Resources, Apr 2022]

Il9 Products (1)

mRNA Protein Name
NM_008373.2 NP_032399.1 interleukin-9 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IGI
IGI: Inferred from genetic interaction
30082831 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within B cell differentiation IGI
IGI: Inferred from genetic interaction
30082831 MGI
acts upstream of or within B cell proliferation IGI
IGI: Inferred from genetic interaction
30082831 MGI
acts upstream of or within immunoglobulin mediated immune response IGI
IGI: Inferred from genetic interaction
30082831 MGI
acts upstream of or within negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IDA
IDA: Inferred from direct assay
18551134 MGI
acts upstream of or within negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IGI
IGI: Inferred from genetic interaction
18551134 MGI
involved in positive regulation of interleukin-5 production IMP
IMP: Inferred from mutant phenotype
16266865 MGI
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
18551134 MGI
acts upstream of or within regulation of peptidyl-tyrosine phosphorylation IGI
IGI: Inferred from genetic interaction
30082831 MGI
acts upstream of or within regulation of receptor signaling pathway via JAK-STAT IDA
IDA: Inferred from direct assay
18551134 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
18997793 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-9

  • T-cell growth factor P40

  • cytokine P40

Recombinant Il9 Proteins

Cat. No. Product Name Accession Purity
HY-P7083 IL-9 Protein, Mouse (CHO, His) P15247 (Q19-P144) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73229 IL-9 Protein, Mouse (sf9, His) P15247 (Q19-P144) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P78319 IL-9 Protein, Mouse (HEK293, Fc) P15247 (Q19-P144) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P700218AF Animal-Free IL-9 Protein, Mouse (His) P15247 (Q19-P144) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-Y0344D Sodium chloride, for cell culture Activator 99.9% Phase 4
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99193 Enokizumab 99.23% Phase 2
HY-P991266 SM-17 Inhibitor 96.98% Phase 2

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-Y0344J Sodium chloride, for molecular biology 99.97% Unkown
HY-Y0344I Sodium chloride, meets analytical specification of Ph. Eur. BP USP, ≤0.00002% Al 99.99% Unkown
HY-161901 BC-1293 Inhibitor 98.40% Unkown
HY-RS06781 IL9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06782 IL9R Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-Y0344H Sodium chloride, United States Pharmacopeia (USP) Reference Standard / Unkown
HY-174595 Human IL9R mRNA / Unkown
HY-174596 Human IL9 mRNA / Unkown
HY-RS17524 Il9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18766 Il9r Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23981 Il9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25254 Il9r Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990208 Anti-Mouse IL-9 Antibody (9C1) Inhibitor 95.00% Unkown
HY-P990206 Anti-Mouse Jagged 2 Antibody (HMJ2-1) Inhibitor / Unkown
HY-P990836 Anti-IL-9 Antibody (MH9A4) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il9 NCBI NCBI:3578