TMEM50A - transmembrane protein 50A Gene

Also Known as SMP1; IFNRC

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23585

Summary

This gene is located in the RH gene locus, between the RHD and RHCE genes. The function of its protein product is unknown; however, its sequence has potential transmembrane domains suggesting that it may be an integral membrane protein. Its position between the RH genes suggests that polymorphisms in this gene may be tightly linked to RH haplotypes and may contribute to selective pressure for or against certain RH haplotypes. [provided by RefSeq, Jul 2008]
Ubiquitous expression in adrenal (RPKM 38.4), colon (RPKM 34.9) and 25 other tissues.

TMEM50A Products (1)

mRNA Protein Name
NM_014313.4 NP_055128.1 transmembrane protein 50A

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM50A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM50A O95807 SLC30A8 Homo sapiens Q8IWU4
Y2H Array
32296183
Intra
TMEM50A O95807 SLC30A8 Homo sapiens Q8IWU4
Y2H Prey Pooling
32296183
Intra
TMEM50A O95807 SLC30A8 Homo sapiens Q8IWU4
Validated Y2H
32296183
Intra
TMEM50A O95807 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
TMEM50A O95807 AQP6 Homo sapiens Q13520
Validated Y2H
32296183
Intra
TMEM50A O95807 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
TMEM50A O95807 LEPROT Homo sapiens O15243
Y2H Array
32296183
Intra
TMEM50A O95807 LEPROT Homo sapiens O15243
Y2H Prey Pooling
32296183
Intra
TMEM50A O95807 HLA-DPA1 Homo sapiens Q95HB9
Y2H Prey Pooling
32296183
Intra
TMEM50A O95807 HLA-DPA1 Homo sapiens Q95HB9
Validated Y2H
32296183
Intra
TMEM50A O95807 HLA-DPA1 Homo sapiens Q95HB9
Y2H Array
32296183
Intra
TMEM50A O95807 SYT9 Homo sapiens Q86SS6
Y2H Prey Pooling
32296183
Intra
TMEM50A O95807 SYT9 Homo sapiens Q86SS6
Validated Y2H
32296183
Intra
TMEM50A O95807 SYT9 Homo sapiens Q86SS6
Y2H Array
32296183
Intra
TMEM50A O95807 COMT Homo sapiens P21964
Validated Y2H
32296183
Intra
TMEM50A O95807 LEPROTL1 Homo sapiens O95214
Y2H Array
32296183
Intra
TMEM50A O95807 LEPROTL1 Homo sapiens O95214
Y2H Prey Pooling
32296183
Intra
TMEM50A O95807 REEP4 Homo sapiens Q9H6H4
Validated Y2H
32296183
Intra
TMEM50A O95807 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
Intra
TMEM50A O95807 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
Intra
TMEM50A O95807 ABCG4 Homo sapiens Q9H172
Validated Y2H
32296183
Intra
TMEM50A O95807 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra
TMEM50A O95807 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra
TMEM50A O95807 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14716 TMEM30A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14729 TMEM50B Human Pre-designed siRNA Set A Pre-designed Set / Unkown