CATIP - ciliogenesis associated TTC17 interacting protein Gene

Also Known as C2orf62

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 375307

About CATIP

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:218,356,857-218,368,094 (from NCBI)

This gene has 5 transcripts (splice variants), 183 orthologues, 1 paralogue and is associated with 1 phenotype. Biased expression in testis (RPKM 1.8), kidney (RPKM 1.1) and 13 other tissues.

Summary

Involved in actin filament polymerization and cilium organization. Located in several cellular components, including actin cytoskeleton; nucleus; and plasma membrane. Implicated in spermatogenic failure. [provided by Alliance of Genome Resources, Apr 2022]

CATIP Products (2)

mRNA Protein Name
NM_001320865.2 NP_001307794.1 ciliogenesis-associated TTC17-interacting protein isoform 1
NM_198559.2 NP_940961.1 ciliogenesis-associated TTC17-interacting protein isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24475127 GOA
Biological Process GO Annotation Evidence References Source
involved in actin filament polymerization IDA
IDA: Inferred from direct assay
32503832 GOA
involved in actin filament polymerization IMP
IMP: Inferred from mutant phenotype
24475127 GOA
involved in cilium organization IMP
IMP: Inferred from mutant phenotype
24475127 GOA
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
24475127 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
24475127 GOA
located in nucleus IDA
IDA: Inferred from direct assay
24475127 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
24475127 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ciliogenesis-associated TTC17-interacting protein

CATIP Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CATIP Q7Z7H3 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
CATIP Q7Z7H3 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra
CATIP Q7Z7H3 KRTAP10-9 Homo sapiens P60411
Y2H Array
25416956
Intra
CATIP Q7Z7H3 KRTAP10-7 Homo sapiens P60409
Validated Y2H
25416956
Intra
CATIP Q7Z7H3 KRTAP10-7 Homo sapiens P60409
Y2H Array
25416956
Intra
CATIP Q7Z7H3 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
Intra
CATIP Q7Z7H3 BRD9 Homo sapiens Q9H8M2
Validated Y2H
25416956
Intra
CATIP Q7Z7H3 MEDAG Homo sapiens Q5VYS4
Y2H Array
32296183
Intra
CATIP Q7Z7H3 MEDAG Homo sapiens Q5VYS4
Y2H Prey Pooling
32296183
Intra
CATIP Q7Z7H3 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
Intra
CATIP Q7Z7H3 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
Intra
CATIP Q7Z7H3 BRD9 Homo sapiens Q9H8M2-3
Y2H Prey Pooling
32296183
Intra
CATIP Q7Z7H3 BRD9 Homo sapiens Q9H8M2-3
Validated Y2H
32296183
Intra
CATIP Q7Z7H3 BRD9 Homo sapiens Q9H8M2-3
Y2H Array
32296183
Intra
CATIP Q7Z7H3 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
CATIP Q7Z7H3 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
CATIP Q7Z7H3 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
CATIP Q7Z7H3 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
CATIP Q7Z7H3 CEP72 Homo sapiens Q9P209
Y2H Array
25416956
Intra
CATIP Q7Z7H3 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
CATIP Q7Z7H3 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra
CATIP Q7Z7H3 MTUS2 Homo sapiens Q5JR59
Y2H Prey Pooling
25416956
Intra
CATIP Q7Z7H3 MTUS2 Homo sapiens Q5JR59
Y2H Array
25416956
Intra
CATIP Q7Z7H3 CTNNBL1 Homo sapiens Q8WYA6
Y2H Prey Pooling
25416956
Intra
CATIP Q7Z7H3 HESX1 Homo sapiens Q9UBX0
Y2H Prey Pooling
32296183
Intra
CATIP Q7Z7H3 HESX1 Homo sapiens Q9UBX0
Validated Y2H
32296183
Intra
CATIP Q7Z7H3 HESX1 Homo sapiens Q9UBX0
Y2H Array
32296183
Intra
CATIP Q7Z7H3 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
CATIP Q7Z7H3 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Intra
CATIP Q7Z7H3 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
CATIP Q7Z7H3 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Intra
CATIP Q7Z7H3 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Spermatogenic Failure 54

  • SPGF54
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Melnick-Needles Syndrome

  • MNS

  • Melnick-Needles Osteodysplasty

  • Osteodysplasty Of Melnick And Needles

  • Osteochondrodysplasias
Male Infertility

  • Infertility, Male

  • Infertility Male

  • Male Sterility

  • Absolute Infertility
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01983 CATIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CATIP RGD RGD:1596071
Mus musculus CATIP MGD MGI:2685062
Bos taurus CATIP VGNC VGNC:26793
Canis familiaris CATIP VGNC VGNC:57375
Felis catus CATIP VGNC VGNC:60392
Macaca mulatta CATIP VGNC VGNC:70624
Others CATIP NCBI