2. Gene
  3. AAK1 - AP2 associated kinase 1 Gene

AAK1 - AP2 associated kinase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 474625 | Gene type: protein coding

About AAK1

Primary_assembly 10: 69,199,727-69,359,723 reverse strand.ROS_Cfam_1.0:CM025109.1

This gene has 8 transcripts (splice variants), 268 orthologues and 2 paralogues.

AAK1 Products(14)

mRNA Protein Name
XM_038680823.1 XP_038536751.1 AP2-associated protein kinase 1 isoform X1
XM_038680828.1 XP_038536756.1 AP2-associated protein kinase 1 isoform X6
XM_038680831.1 XP_038536759.1 AP2-associated protein kinase 1 isoform X9
XM_038680826.1 XP_038536754.1 AP2-associated protein kinase 1 isoform X4
XM_038680825.1 XP_038536753.1 AP2-associated protein kinase 1 isoform X3
XM_038680836.1 XP_038536764.1 AP2-associated protein kinase 1 isoform X14
XM_038680829.1 XP_038536757.1 AP2-associated protein kinase 1 isoform X7
XM_038680827.1 XP_038536755.1 AP2-associated protein kinase 1 isoform X5
XM_038680830.1 XP_038536758.1 AP2-associated protein kinase 1 isoform X8
XM_038680834.1 XP_038536762.1 AP2-associated protein kinase 1 isoform X12
XM_038680833.1 XP_038536761.1 AP2-associated protein kinase 1 isoform X11
XM_038680824.1 XP_038536752.1 AP2-associated protein kinase 1 isoform X2
XM_038680835.1 XP_038536763.1 AP2-associated protein kinase 1 isoform X13
XM_038680832.1 XP_038536760.1 AP2-associated protein kinase 1 isoform X10

AAK1 Protein Structure

STKc_NAK_like

STKc_NAK_like: cd14037 (41 - 315)

DUF5585

DUF5585: cl39316 (319 - 418)

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  • 952 a.a.
Protein Preferred Names Protein Names

AP2-associated protein kinase 1

LOW QUALITY PROTEIN: AP2-associated protein kinase 1

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-134829 BMS-986176 98.85% Phase 2
Pre-clinical Phase
Bioactive Molecules (35)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-117626 LP-935509 Inhibitor 99.74% Unkown
HY-123940 SGC-AAK1-1 98.47% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-171770 dAurAB5 Inhibitor 99.03% Unkown
HY-120179 LP-922761 98.21% Unkown
HY-101290A BMT-090605 hydrochloride Inhibitor 98.76% Unkown
HY-148062 RSS0680 98.03% Unkown
HY-115868 BMS-911172 99.49% Unkown
HY-135871 BMT-124110 99.15% Unkown
HY-148063 DB0614 96.07% Unkown
HY-149054 GSK-3β inhibitor 13 Inhibitor 99.74% Unkown
HY-147083 SGC-AAK1-1N Inhibitor 97.9% Unkown
HY-135871A BMT-124110 formic Inhibitor / Unkown
HY-117453 BMS-901715 / Unkown
HY-120179A LP-922761 hydrate 98.0% Unkown
HY-181293 PROTAC AAK1 degrader-1 Degrader / Unkown
HY-176705 AAK1-IN-9 Inhibitor / Unkown
HY-162388 TIM-098a Inhibitor / Unkown
HY-145838 AAK1-IN-4 / Unkown
HY-161261 SARS-CoV-2-IN-81 Inhibitor / Unkown
HY-144301 AAK1-IN-2 / Unkown
HY-144302A AAK1-IN-3 TFA / Unkown
HY-185187 AAK1-IN-12 Inhibitor / Unkown
HY-176706 AAK1-IN-10 Inhibitor / Unkown
HY-144302 AAK1-IN-3 / Unkown
HY-101290 BMT-090605 Inhibitor 98.27% Unkown
HY-159931 HW161023 Inhibitor / Unkown
HY-145839 AAK1-IN-5 / Unkown
HY-144301A AAK1-IN-2 TFA / Unkown
HY-169405 AAK1/HDACs-IN-1 Inhibitor / Unkown
HY-174213 AAK1-IN-7 Inhibitor / Unkown
HY-175536 AAK1-IN-11 Inhibitor / Unkown
HY-174214 AAK1-IN-8 Inhibitor / Unkown
HY-159879 AAK1-IN-6 Inhibitor / Unkown
HY-120092 BMT-046091 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens AAK1 NCBI NCBI:22848