AAK1 - AP2 associated kinase 1 Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 474625
About AAK1
Primary_assembly 10: 69,199,727-69,359,723 reverse strand.ROS_Cfam_1.0:CM025109.1
This gene has 8 transcripts (splice variants), 268 orthologues and 2 paralogues.
AAK1 Products (14)
| mRNA | Protein | Name |
|---|---|---|
| XM_038680823.1 | XP_038536751.1 | AP2-associated protein kinase 1 isoform X1 |
| XM_038680828.1 | XP_038536756.1 | AP2-associated protein kinase 1 isoform X6 |
| XM_038680831.1 | XP_038536759.1 | AP2-associated protein kinase 1 isoform X9 |
| XM_038680826.1 | XP_038536754.1 | AP2-associated protein kinase 1 isoform X4 |
| XM_038680825.1 | XP_038536753.1 | AP2-associated protein kinase 1 isoform X3 |
| XM_038680836.1 | XP_038536764.1 | AP2-associated protein kinase 1 isoform X14 |
| XM_038680829.1 | XP_038536757.1 | AP2-associated protein kinase 1 isoform X7 |
| XM_038680827.1 | XP_038536755.1 | AP2-associated protein kinase 1 isoform X5 |
| XM_038680830.1 | XP_038536758.1 | AP2-associated protein kinase 1 isoform X8 |
| XM_038680834.1 | XP_038536762.1 | AP2-associated protein kinase 1 isoform X12 |
| XM_038680833.1 | XP_038536761.1 | AP2-associated protein kinase 1 isoform X11 |
| XM_038680824.1 | XP_038536752.1 | AP2-associated protein kinase 1 isoform X2 |
| XM_038680835.1 | XP_038536763.1 | AP2-associated protein kinase 1 isoform X13 |
| XM_038680832.1 | XP_038536760.1 | AP2-associated protein kinase 1 isoform X10 |
AAK1 Protein Structure
STKc_NAK_like
STKc_NAK_like: cd14037 (41 - 315)
DUF5585
DUF5585: cl39316 (319 - 418)
- 0
- 200
- 400
- 600
- 800
- 952 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
AP2-associated protein kinase 1 LOW QUALITY PROTEIN: AP2-associated protein kinase 1 |
|
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-134829 | BMS-986176 | 98.85% | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(35)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-117626 | LP-935509 | Inhibitor | 99.74% | Unkown |
| HY-123940 | SGC-AAK1-1 | 98.47% | Unkown | |
| HY-148065 | FMF-06-098-1 | Inhibitor | 98.77% | Unkown |
| HY-171770 | dAurAB5 | Inhibitor | 99.03% | Unkown |
| HY-101290A | BMT-090605 hydrochloride | Inhibitor | 98.76% | Unkown |
| HY-120179 | LP-922761 | 98.21% | Unkown | |
| HY-148062 | RSS0680 | 98.03% | Unkown | |
| HY-115868 | BMS-911172 | 99.49% | Unkown | |
| HY-135871 | BMT-124110 | 99.15% | Unkown | |
| HY-148063 | DB0614 | 96.07% | Unkown | |
| HY-149054 | GSK-3β inhibitor 13 | Inhibitor | 99.74% | Unkown |
| HY-147083 | SGC-AAK1-1N | Inhibitor | 97.9% | Unkown |
| HY-135871A | BMT-124110 formic | Inhibitor | / | Unkown |
| HY-117453 | BMS-901715 | / | Unkown | |
| HY-120179A | LP-922761 hydrate | 98.0% | Unkown | |
| HY-181293 | PROTAC AAK1 degrader-1 | Degrader | / | Unkown |
| HY-176705 | AAK1-IN-9 | Inhibitor | / | Unkown |
| HY-162388 | TIM-098a | Inhibitor | / | Unkown |
| HY-145838 | AAK1-IN-4 | / | Unkown | |
| HY-161261 | SARS-CoV-2-IN-81 | Inhibitor | / | Unkown |
| HY-144301 | AAK1-IN-2 | / | Unkown | |
| HY-144302A | AAK1-IN-3 TFA | / | Unkown | |
| HY-185187 | AAK1-IN-12 | Inhibitor | / | Unkown |
| HY-176706 | AAK1-IN-10 | Inhibitor | / | Unkown |
| HY-144302 | AAK1-IN-3 | / | Unkown | |
| HY-101290 | BMT-090605 | Inhibitor | 98.27% | Unkown |
| HY-159931 | HW161023 | Inhibitor | / | Unkown |
| HY-145839 | AAK1-IN-5 | / | Unkown | |
| HY-144301A | AAK1-IN-2 TFA | / | Unkown | |
| HY-169405 | AAK1/HDACs-IN-1 | Inhibitor | / | Unkown |
| HY-174213 | AAK1-IN-7 | Inhibitor | / | Unkown |
| HY-175536 | AAK1-IN-11 | Inhibitor | / | Unkown |
| HY-174214 | AAK1-IN-8 | Inhibitor | / | Unkown |
| HY-159879 | AAK1-IN-6 | Inhibitor | / | Unkown |
| HY-120092 | BMT-046091 | Inhibitor | / | Unkown |
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