2. Gene
  3. TRA2B - transformer 2 beta homolog Gene

TRA2B - transformer 2 beta homolog Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SFRS10; SRFS10; TRAN2B; PPP1R156; TRA2-BETA; Htra2-beta

Gene ID: 6434 | Gene type: protein coding

About TRA2B

Cytogenetic location: 3q27.2 Genomic coordinates (GRCh38): 3:185,914,558-185,938,014 (from NCBI)

This gene has 15 transcripts (splice variants), 542 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 41.9), lymph node (RPKM 15.3) and 25 other tissues.

Summary

This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

TRA2B Products(2)

mRNA Protein Name
NM_001243879.2 NP_001230808.1 transformer-2 protein homolog beta isoform 2
NM_004593.3 NP_004584.1 transformer-2 protein homolog beta isoform 1

TRA2B Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (122 - 190)

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  • 288 a.a.
Protein Preferred Names Protein Names

transformer-2 protein homolog beta

TRA-2 beta

Recombinant TRA2B Proteins

Cat. No. Product Name Accession Purity
HY-P72056 TRA2B Protein, Human (Baculovirus, His-Myc) P62995 (S2-Y288) ≥95%

Related Diseases

Diseases Alias
Spinal Muscular Atrophy

Sma

5q Sma

Proximal Sma

Sma-Associated Sma

Spinal Amyotrophies

Spinal Amyotrophy

Spinal Muscle Degeneration

Spinal Muscle Wasting

Muscular Atrophy Spinal

Atrophy, Muscular, Spinal

Hereditary Motor Neuronopathy

Progressive Muscular Atrophy

Sma - [Spinal Muscular Atrophy]
Muscular Atrophy

Muscle Wasting

Amyotrophia

Wasting - Muscle

Skeletal Muscle Atrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14962 TRA2B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TRA2B VGNC VGNC:47759
Felis catus TRA2B VGNC VGNC:66491
Bos taurus TRA2B VGNC VGNC:36268
Macaca mulatta TRA2B VGNC VGNC:78554
Rattus norvegicus TRA2B RGD RGD:619886
Mus musculus TRA2B MGD MGI:106016
Others TRA2B NCBI