SIRAL1 - SIR2 antiphage like 1 Gene

Also Known as SIRal; FAM118B

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79607

Summary

Enables identical protein binding activity. Predicted to be located in Cajal body. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in thyroid (RPKM 26.8), salivary gland (RPKM 21.2) and 25 other tissues.

SIRAL1 Products (1)

mRNA Protein Name
NG_017156.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SIRAL1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FAM118B Q9BPY3 PIAS2 Homo sapiens O75928-2
Y2H Array
32296183
Intra
FAM118B Q9BPY3 PIAS2 Homo sapiens O75928-2
Y2H Prey Pooling
32296183
Intra
FAM118B Q9BPY3 BAG5 Homo sapiens Q9UL15
Validated Y2H
25416956
Intra
FAM118B Q9BPY3 BAG5 Homo sapiens Q9UL15
Y2H Prey Pooling
25416956
Intra
FAM118B Q9BPY3 RAD54L2 Homo sapiens Q9Y4B4
Validated Y2H
32296183
Intra
FAM118B Q9BPY3 FAM118B Homo sapiens Q9BPY3
Y2H Prey Pooling
32296183
Intra
FAM118B Q9BPY3 FAM118A Homo sapiens Q9NWS6
Validated Y2H
32296183
Intra
FAM118B Q9BPY3 PDCD10 Homo sapiens Q9BUL8
Y2H Prey Pooling
32296183
Intra
FAM118B Q9BPY3 SDCBP Homo sapiens O00560
Y2H Prey Pooling
25416956
Intra
FAM118B Q9BPY3 RAD54L2 Homo sapiens Q9Y4B4
Y2H Prey Pooling
32296183
Intra
FAM118B Q9BPY3 PDCD10 Homo sapiens Q9BUL8
Y2H Array
32296183
Intra
FAM118B Q9BPY3 SUMO1 Homo sapiens P63165
Validated Y2H
25416956
Intra
FAM118B Q9BPY3 FAM118B Homo sapiens Q9BPY3
Validated Y2H
32296183
Intra
FAM118B Q9BPY3 PDCD10 Homo sapiens Q9BUL8
Validated Y2H
32296183
Intra
FAM118B Q9BPY3 RAD54L2 Homo sapiens Q9Y4B4
Y2H Array
32296183
Intra
FAM118B Q9BPY3 FAM118B Homo sapiens Q9BPY3
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-157039 RIPK1-IN-17 Inhibitor 97.09% Unkown
HY-153435 RIP1 kinase inhibitor 5 Inhibitor 98.49% Unkown