Dgkz - diacylglycerol kinase zeta Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81821

Summary

Enables diacylglycerol kinase activity. Predicted to be involved in several processes, including glycerolipid metabolic process; lipid phosphorylation; and maintenance of postsynaptic density structure. Predicted to act upstream of or within negative regulation of Ras protein signal transduction. Located in nucleus. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human DGKZ (diacylglycerol kinase zeta). [provided by Alliance of Genome Resources, Apr 2022]

Dgkz Products (1)

mRNA Protein Name
NM_031143.2 NP_112405.1 diacylglycerol kinase zeta

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables ATP-dependent diacylglycerol kinase activity IDA
IDA: Inferred from direct assay
8855332 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15157668 RGD
Cellular Component GO Annotation Evidence Verweise Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
19229292 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
19229292 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

diacylglycerol kinase zeta

  • 104 kDa diacylglycerol kinase

  • DAG kinase zeta

  • DGK-IV

  • DGK-zeta

  • diglyceride kinase zeta

Dgkz Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Dgkz O08560 Dlg3 Rattus norvegicus Q62936
Anti Tag CoIP
19229292
Intra
Dgkz O08560 Dlg3 Rattus norvegicus Q62936
Anti Bait CoIP
19229292
Intra
Dgkz O08560 Dlg4 Rattus norvegicus P31016
Anti Bait CoIP
19229292
Intra
Dgkz O08560 Dlg4 Rattus norvegicus P31016
Y2H
19229292
Intra
Dgkz O08560 Dlg1 Rattus norvegicus Q62696
Y2H
19229292
Intra
Dgkz O08560 Dlg1 Rattus norvegicus Q62696
Anti Tag CoIP
19229292
Intra
Dgkz O08560 Dlg1 Rattus norvegicus Q62696
Anti Bait CoIP
19229292
Intra
Dgkz O08560 Dlg2 Rattus norvegicus Q63622
Anti Tag CoIP
19229292
Intra
Dgkz O08560 Dlg2 Rattus norvegicus Q63622
Anti Bait CoIP
19229292
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-135898 DGK-IN-1 Inhibitor 98.67% Unkown
HY-RS03724 DGKZ Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dgkz NCBI NCBI:8525