PRPF38A - pre-mRNA processing factor 38A Gene

Also Known as Prp38; PRP38A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84950

Summary

Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in lymph node (RPKM 12.2), ovary (RPKM 11.7) and 25 other tissues.

PRPF38A Products (1)

mRNA Protein Name
NM_032864.4 NP_116253.2 pre-mRNA-splicing factor 38A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22365833 GOA
Biological Process GO Annotation Evidence References Source
involved in mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
28781166 GOA
involved in mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
26673105 GOA
Cellular Component GO Annotation Evidence References Source
part of U2-type precatalytic spliceosome IDA
IDA: Inferred from direct assay
28781166 GOA
located in nucleus IDA
IDA: Inferred from direct assay
28781166 GOA
part of precatalytic spliceosome IDA
IDA: Inferred from direct assay
26673105 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRPF38A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PRPF38A Q8NAV1 AP2M1 Homo sapiens Q96CW1
Y2H Prey Pooling
32296183
Intra
PRPF38A Q8NAV1 AP2M1 Homo sapiens Q96CW1
Validated Y2H
32296183
Intra
PRPF38A Q8NAV1 AP2M1 Homo sapiens Q96CW1
Y2H Array
32296183
Intra
PRPF38A Q8NAV1 SRSF7 Homo sapiens Q16629
Y2H Prey Pooling
32296183
Intra
PRPF38A Q8NAV1 SRSF7 Homo sapiens Q16629
Y2H Array
32296183
Intra
PRPF38A Q8NAV1 SRPK1 Homo sapiens Q96SB4
Protein Kinase Assay
23602568
Intra
PRPF38A Q8NAV1 SRPK2 Homo sapiens P78362
Y2H Prey Pooling
25416956
Intra
PRPF38A Q8NAV1 SRPK2 Homo sapiens P78362
Validated Y2H
25416956
Intra
PRPF38A Q8NAV1 SDCBP Homo sapiens O00560
Y2H Array
25416956
Intra
PRPF38A Q8NAV1 SDCBP Homo sapiens O00560
Validated Y2H
25416956
Intra
PRPF38A Q8NAV1 DVL3 Homo sapiens Q92997
Y2H Prey Pooling
32296183
Intra
PRPF38A Q8NAV1 DVL3 Homo sapiens Q92997
Validated Y2H
32296183
Intra
PRPF38A Q8NAV1 DVL3 Homo sapiens Q92997
Y2H Array
32296183
Intra
PRPF38A Q8NAV1 SDCBP2 Homo sapiens Q9H190
Validated Y2H
32296183
Intra
PRPF38A Q8NAV1 SDCBP2 Homo sapiens Q9H190
Validated Y2H
25416956
Intra
PRPF38A Q8NAV1 SDCBP2 Homo sapiens Q9H190
Y2H Array
32296183
Intra
PRPF38A Q8NAV1 SDCBP2 Homo sapiens Q9H190
Y2H Array
25416956
Intra
PRPF38A Q8NAV1 SDCBP2 Homo sapiens Q9H190
Y2H Prey Pooling
25416956
Intra
PRPF38A Q8NAV1 SDCBP2 Homo sapiens Q9H190
Y2H Prey Pooling
32296183
Intra
PRPF38A Q8NAV1 SDCBP2 Homo sapiens Q9H190
Y2H Array
31515488
Intra
PRPF38A Q8NAV1 CLK2 Homo sapiens P49760
Y2H Array
25416956
Intra
PRPF38A Q8NAV1 JMJD6 Homo sapiens Q6NYC1
Anti Tag CoIP
23455924
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11209 PRPF38B Human Pre-designed siRNA Set A Pre-designed Set / Unkown