BCL10 - BCL10 immune signaling adaptor Gene

Also Known as CLAP; mE10; CIPER; IMD37; c-E10; CARMEN

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 8915

About BCL10

Cytogenetic location: 1p22.3 Genomic coordinates (GRCh38): 1:85,265,776-85,276,632 (from NCBI)

This gene has 5 transcripts (splice variants), 100 orthologues and is associated with 56 phenotypes. Ubiquitous expression in colon (RPKM 9.9), gall bladder (RPKM 8.1) and 25 other tissues.

Summary

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a Caspase recruitment domain (CARD), and has been shown to induce Apoptosis and to activate NF-kappaB. This protein is reported to interact with Other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

BCL10 Products (2)

mRNA	Protein	Name
NM_001320715.2	NP_001307644.1	B-cell lymphoma/leukemia 10 isoform 2
NM_003921.5	NP_003912.1	B-cell lymphoma/leukemia 10 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables NF-kappaB binding	IDA IDA: Inferred from direct assay	16280327	GOA
enables general transcription initiation factor binding	IPI IPI: Inferred from physical interaction	15207693	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	10187771	GOA
contributes to kinase activator activity	IDA IDA: Inferred from direct assay	15125833	GOA
enables protease binding	IPI IPI: Inferred from physical interaction	18223652	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	10187771	GOA
enables protein kinase B binding	IPI IPI: Inferred from physical interaction	16280327	GOA
enables protein-macromolecule adaptor activity	IDA IDA: Inferred from direct assay	15125833	GOA
enables transcription coactivator activity	IDA IDA: Inferred from direct assay	15207693	GOA
enables ubiquitin protein ligase binding	IPI IPI: Inferred from physical interaction	16395405	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in T cell receptor signaling pathway	IDA IDA: Inferred from direct assay	15125833	GOA
involved in adaptive immune response	IMP IMP: Inferred from mutant phenotype	25365219	GOA
involved in cellular response to lipopolysaccharide	IEP IEP: Inferred from expression pattern	16831874	GOA
involved in cellular response to mechanical stimulus	IEP IEP: Inferred from expression pattern	19593445	GOA
involved in innate immune response	IEP IEP: Inferred from expression pattern	16831874	GOA
involved in lipopolysaccharide-mediated signaling pathway	IDA IDA: Inferred from direct assay	16831874	GOA
involved in negative regulation of mature B cell apoptotic process	IDA IDA: Inferred from direct assay	15878976	GOA
involved in positive regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	15207693	GOA
involved in positive regulation of NF-kappaB transcription factor activity	IDA IDA: Inferred from direct assay	10400625	GOA
involved in positive regulation of T cell receptor signaling pathway	IDA IDA: Inferred from direct assay	18287044	GOA
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	11821383	GOA
involved in positive regulation of canonical NF-kappaB signal transduction	IDA IDA: Inferred from direct assay	18287044	GOA
involved in positive regulation of canonical NF-kappaB signal transduction	IEP IEP: Inferred from expression pattern	12761501	GOA
involved in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP IMP: Inferred from mutant phenotype	22267217	GOA
involved in positive regulation of extrinsic apoptotic signaling pathway	IDA IDA: Inferred from direct assay	11466612	GOA
involved in positive regulation of interleukin-8 production	IMP IMP: Inferred from mutant phenotype	17095757	GOA
involved in positive regulation of phosphorylation	IDA IDA: Inferred from direct assay	15125833	GOA
involved in positive regulation of protein ubiquitination	IDA IDA: Inferred from direct assay	14695475	GOA
involved in programmed cell death	IDA IDA: Inferred from direct assay	10400625	GOA
involved in protein homooligomerization	IDA IDA: Inferred from direct assay	24074955	GOA
involved in response to food	IDA IDA: Inferred from direct assay	17095757	GOA
involved in toll-like receptor signaling pathway	IDA IDA: Inferred from direct assay	16831874	GOA

Cellular Component GO Annotation	Evidence	References	Source
part of CBM complex	IDA IDA: Inferred from direct assay	24074955	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	11021819	GOA
located in cytoplasmic microtubule	IDA IDA: Inferred from direct assay	23264731	GOA
located in cytosol	IDA IDA: Inferred from direct assay	12154360	GOA
located in lysosome	IDA IDA: Inferred from direct assay	15082780	GOA
located in nucleus	IDA IDA: Inferred from direct assay	16280327	GOA
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	16127295	GOA
part of protein-containing complex	IDA IDA: Inferred from direct assay	14695475	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BCL10 Protein Structure

CARD

0
100
200
233 a.a.

Protein Preferred Names	Protein Names
B-cell lymphoma/leukemia 10	B cell CLL/lymphoma 10

BCL10 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	BCL10	O95999	MALT1	Homo sapiens	Q9UDY8	Anti Tag CoIP	33961781
Intra	BCL10	O95999	MALT1	Homo sapiens	Q9UDY8	Anti Bait CoIP	31774199
Intra	BCL10	O95999	MALT1	Homo sapiens	Q9UDY8	Anti Bait CoIP	21157432
Intra	BCL10	O95999	MALT1	Homo sapiens	Q9UDY8	Anti Bait CoIP	22267217
Intra	BCL10	O95999	MALT1	Homo sapiens	Q9UDY8	Anti Bait CoIP	19118383
Intra	BCL10	O95999	MALT1	Homo sapiens	Q9UDY8	Anti Bait CoIP	17948050
Intra	BCL10	O95999	MALT1	Homo sapiens	Q9UDY8	Anti Tag CoIP	22528498
Intra	BCL10	O95999	CARD14	Homo sapiens	Q9BXL6-2	Anti Tag CoIP	27071417
Intra	BCL10	O95999	AKT1	Homo sapiens	P31749	Anti Bait CoIP	16280327
Intra	BCL10	O95999	TRAF2	Homo sapiens	Q12933	Anti Tag CoIP	33961781
Intra	BCL10	O95999	TRAF2	Homo sapiens	Q12933	Y2H Bait-Prey Pool	25910212
Intra	BCL10	O95999	TRAF2	Homo sapiens	Q12933	Y2H Array	32296183
Intra	BCL10	O95999	TRAF2	Homo sapiens	Q12933	Validated Y2H	25910212
Intra	BCL10	O95999	TRAF2	Homo sapiens	Q12933	Y2H Array	25910212
Intra	BCL10	O95999	TRAF2	Homo sapiens	Q12933	Validated Y2H	25416956
Intra	BCL10	O95999	TRAF2	Homo sapiens	Q12933	Y2H Prey Pooling	32296183
Intra	BCL10	O95999	TRAF2	Homo sapiens	Q12933	Validated Y2H	32296183
Intra	BCL10	O95999	COG6	Homo sapiens	Q9Y2V7	BFG-2H	27107012
Intra	BCL10	O95999	COG6	Homo sapiens	Q9Y2V7	Y2H Array	32296183
Intra	BCL10	O95999	COG6	Homo sapiens	Q9Y2V7	Validated Y2H	32296183
Intra	BCL10	O95999	COG6	Homo sapiens	Q9Y2V7	Y2H Prey Pooling	32296183
Intra	BCL10	O95999	CARD14	Homo sapiens	Q9BXL6-1	Anti Tag CoIP	27071417
Intra	BCL10	O95999	CARD11	Homo sapiens	Q9BXL7	Anti Bait CoIP	21157432
Intra	BCL10	O95999	CARD11	Homo sapiens	Q9BXL7	Anti Bait CoIP	17948050
Intra	BCL10	O95999	CARD11	Homo sapiens	Q9BXL7	Anti Bait CoIP	19118383
Intra	BCL10	O95999	CARD11	Homo sapiens	Q9BXL7	Anti Bait CoIP	19815501
Intra	BCL10	O95999	CARD9	Homo sapiens	Q9H257	Anti Bait CoIP	22267217
Intra	BCL10	O95999	IKBKG	Homo sapiens	Q9Y6K9	Anti Bait CoIP	27070702
Intra	BCL10	O95999	IKBKG	Homo sapiens	Q9Y6K9	Anti Tag CoIP	27070702
Intra	BCL10	O95999	IKBKG	Homo sapiens	Q9Y6K9	Anti Tag CoIP	18287044
Intra	BCL10	O95999	IKBKG	Homo sapiens	Q9Y6K9	Anti Bait CoIP	18287044
Intra	BCL10	O95999	BCL3	Homo sapiens	P20749	Anti Bait CoIP	16280327

Cross: Cross-species interaction Intra: Intraspecies interaction

BCL10 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81443	Bcl-10 Antibody (YA1188)	IHC-P	Human
HY-P81443A	Bcl-10 Antibody (YA1188)(PBS only)	IHC-P	Human
HY-P83882	Bcl-10 Antibody (YA3579)	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse
HY-P83882A	Bcl-10 Antibody (YA3579)(PBS only)	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse

Related Diseases

Diseases	Alias
Lymphoma, Mucosa-Associated Lymphoid Type	Malt Lymphoma Gastric Lymphoma, Primary Lymphoma, Malt, Somatic Mucosa-Associated Lymphoid Tissue Lymphoma Extranodal Marginal Zone B-Cell Lymphoma MALTOMA Marginal Zone B-Cell Lymphoma Mucosa-Associated Lymphatic Tissue Lymphoma Primary Gastric Lymphoma Gastric Lymphoma Familial Primary Gastric Lymphoma
Mesothelioma, Malignant	Malignant Mesothelioma Pleural Mesothelioma MESOM Mesothelioma, Somatic Advanced Malignant Mesothelioma Asbestos-Related Malignant Mesothelioma Diffuse Malignant Mesothelioma Malignant Tumor Of Mesothelium Malignant Mesothelioma, Susceptibility To Mesothelioma Diffuse Malignant Mesothelioma Malignant Pleural Mesothelioma
Immunodeficiency 37	IMD37 Immunodeficiency, Type 37
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Testicular Germ Cell Tumor	Male Germ Cell Tumor Testicular Teratoma TGCT Mgct Male Germ Cell Tumor, Somatic Spermatocytic Seminoma, Somatic Embryonal Cell Carcinoma Seminoma Spermatocytic Seminoma Germ Cell Tumors, Somatic Testicular Tumor, Somatic Non-Seminomatous Germ Cell Tumor Of Testis Non-Dysgerminomatous Germ Cell Tumor Of Testis Testicular Non Seminomatous Germ Cell Tumor Testicular Non-Dysgerminomatous Germ Cell Tumor Teratoma Of The Testis Endodermal Sinus Tumor Nonseminomatous Germ Cell Tumors Teratoma Testicular Germ Cell Tumor, Somatic Embryonal Carcinoma Cell Yolk Sac Tumor Malignant Testicular Non-Seminomatous Germ Cell Tumor Testicular Non-Seminomatous Germ Cell Tumor Teratoma Of Testis Nonseminomatous Germ Cell Tumor
Follicular Lymphoma	Lymphoma, Follicular Lymphoma Follicular Brill-Symmers' Disease Large Cell Follicular Non-Hodgkin Lymphoma Diffuse Follicle Centre Lymphoma Diffuse Follicular Lymphoma Nos Follicular Nodular Non-Hodgkin Lymphoma, Unspecified Follicular Large Cell Cleaved Or Noncleaved Lymphoma Large Cell Follicular Noncleaved Lymphoma Follicular Lymphoma With Or Without Diffuse Areas Histiocytic Follicular Lymphoma Histiocytic Nodular Lymphoma Histiocytic Nodular Malignant Lymphoma Large Cell Follicular Lymphoma Large Cell Noncleaved Follicular Lymphoma Large Cell Noncleaved Follicular Malignant Lymphoma Nodular Reticulum Cell Sarcoma Noncleaved Follicular Lymphoma
Sezary'S Disease	Sezary Syndrome Sézary Syndrome Sezary'S Lymphoma Sezary Disease Sezary Erythroderma Sezary Lymphoma
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Testicular Cancer	Testis Cancer Testicular Carcinoma Testicular Neoplasms Malignant Neoplasm Of Testis Childhood Neoplasm Of The Testis Neoplasm Of Testis Pediatric Testicular Neoplasm Testicular Tumor Testis Neoplasm Testicular Tumors Testicular Neoplasm Testicular Malignant Germ Cell Tumor Childhood Testicular Neoplasm Carcinoma Of The Testis Cancer Of Testis Malignant Neoplasm Of Testis, Nos Malignant Neoplasm Of Testis, Unspecified Malignant Tumour Of Testis Testicle Cancer Primary Malignant Neoplasm Of Testis
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Testicular Germ Cell Cancer	Germ Cell Tumor Of Testis Testicular Germ Cell Tumor Testicular Germ Cell Neoplasm Testicular Malignant Germ Cell Tumor
Lymphoma	Lymphoid Cancer Lymphomas Lymphoid Cancers Lymphoid Neoplasm Lymphoma Nos Nhl - [Non-Hodgkin Lymphoma] Non-Hodgkin Lymphoma Non-Hodgkin Lymphoma, Nos Non-Hodgkin Malignant Lymphoma Nos
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Gastric Lymphoma	Familial Primary Gastric Lymphoma Lymphoma Of The Stomach Primary Gastric Lymphoma
Combined Immunodeficiency	Combined T Cell And B Cell Immunodeficiency Congenital Combined Immunodeficiency Syndrome With Combined Immunodeficiency Combined T And B Cell Immunodeficiency Combined Immunity Deficiency Combined Immunodeficiency Syndrome Combined T-Cell And B-Cell Immunodeficiency Lymphopenic Agammaglobulinaemia
Immunodeficiency 11	Immunodeficiency 11a Severe Combined Immunodeficiency Due To Card11 Deficiency IMD11A Imd11 Card11 Immunodeficiency Scid Due To Card11 Deficiency Card11 Deficiency Immunodeficiency 11 A
Pancreatic Acinar Cell Adenocarcinoma	Pancreatic Acinar Cell Carcinoma Acinar Cell Adenocarcinoma Of The Pancreas
Overnutrition
Alpha Chain Disease	Seligmann'S Disease Immunoproliferative Small Intestinal Disease
Marginal Zone B-Cell Lymphoma	Marginal Zone Lymphoma Mzl Mucosa-Associated Lymphoid Tissue Lymphoma
Leukemia	Leukemias Leukaemia, Unspecified, Without Mention Of Remission Aleukemic Leukaemia Chronic Leukaemia Subacute Leukaemia Leukaemia Disorder Leukaemia Nos
Orbit Lymphoma	Orbital Lymphoma Lymphoma Of The Orbit
Phaeohyphomycosis	Infection By Dematiacious Fungi Phaehyphomycosis Phaeomycosis Pheohyphomycosis Infection By Dematiacious Fungi [Phaehyphomycosis] Dematiaceous Fungal Infection
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Pancreatoblastoma
Orofaciodigital Syndrome Viii	Edwards Syndrome Trisomy 18 Complete Trisomy 18 Syndrome OFD8 Orofaciodigital Syndrome 8 Trisomy 18 Syndrome Oral-Facial-Digital Syndrome With Hypoplastic Epiglottis E3 Trisomy Oral-Facial-Digital Syndrome Type 8 Orofaciodigital Syndrome Type 8 Ofds Viii Oral-Facial-Digital Syndrome, Type Viii Ofd Syndrome 8 Ofds 8 Oral Facial Digital Syndrome 8 Oral Facial Digital Syndrome Type 8 18 Trisomy Chromosome 18 Trisomy Trisomy 16-18 Trisomy E Trisomy E Syndrome Chromosome 18 Duplication Oral-Facial-Digital Syndrome, Edwards Type Orofaciodigital Syndrome, Edwards Type Chromosome 18, Trisomy Cleft Lip/Palate With Abnormal Thumbs And Microcephaly Trisomy 18 Chromosome Abnormal Autosomes 18
Nodal Marginal Zone Lymphoma	Mucosa-Associated Lymphoid Tissue Lymphoma Monocytoid B-Cell Lymphoma
Severe Combined Immunodeficiency	Scid Severe Combined Immunodeficiency Disease Combined T And B Cell Inborn Immunodeficiency Immunodeficiency, Severe Combined Scid - [Severe Combined Immunodeficiencies]
Acinar Cell Carcinoma	Acinic Cell Carcinoma Acinic Cell Tumor Carcinoma Acinar Cell Carcinoma, Acinar Cell Acinar Cell Tumor
Gastrointestinal Lymphoma
Dermatophytosis	Tinea Dermatophytosis, Unspecified Ringworm Infections Due To Species Of Epidermophyton, Microsporum And Trichophyton Cutaneous Mycosis Dermal Mycosis Superficial Mycosis, Unspecified Fungus Infection Of Skin Skin Mycosis Dermatitis Fungoid Fungal Dermatitis Fungal Dermatosis Mycotic Infection Of Skin
Chronic Mucocutaneous Candidiasis	Candidiasis, Chronic Mucocutaneous Cmc Candidiasis Chronic Mucocutaneous
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Noonan Syndrome 1	Noonan Syndrome NS1 Male Turner Syndrome Female Pseudo-Turner Syndrome Turner Phenotype With Normal Karyotype Noonan Syndrome With Pigmented Villonodular Synovitis Turner'S Phenotype, Karyotype Normal Familial Turner Syndrome Noonan'S Syndrome Noonan-Ehmke Syndrome Ns Pseudo-Ullrich-Turner Syndrome Turner Syndrome In Female With X Chromosome Turner-Like Syndrome Ullrich-Noonan Syndrome Noonan-Like/Multiple Giant Cell Lesion Syndrome Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions Pterygium Colli Syndrome Noonan Syndrome, Type 1 Turner Syndrome, Male
Mantle Cell Lymphoma	Lymphoma, Mantle Cell Lcm Mcl Mantle Zone Lymphoma Lymphoma Mantle-Cell Lymphoma, Mantle-Cell Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse Malignant Lymphoma - Lymphocytic, Intermediate Differentiation Diffuse Small Cleaved-Cell Lymphoma Diffuse Small Cleaved Cell Malignant Lymphoma Small Cleaved Cell Non-Hodgkin Lymphoma Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma Malignant Lymphomatous Polyposis Malignant Small Cell, Noncleaved, Diffuse Lymphoma Malignant Undifferentiated Cell, Non-Burkitt Lymphoma Cleaved Cell Lymphoma Small Cell Mantle Cell Lymphoma Small Cleaved Cell Malignant Lymphoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-142648	MLT-985	Inhibitor	99.49%	Unkown
HY-174371	INNO-220		98.60%	Unkown
HY-131902	MLT-231	Inhibitor	99.55%	Unkown
HY-142648A	(R)-MLT-985	Inhibitor	/	Unkown
HY-RS01412	BCL10 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS17823	Bcl10 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24291	Bcl10 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	BCL10	VGNC	VGNC:80147
Rattus norvegicus	BCL10	RGD	RGD:620544
Mus musculus	BCL10	MGD	MGI:1337994
Canis familiaris	BCL10	VGNC	VGNC:57980
Macaca mulatta	BCL10	VGNC	VGNC:70240
Bos taurus	BCL10	VGNC	VGNC:53853
Others	BCL10	NCBI