Gln-Leu
Gln-Leu is an orally active Acetylcholinesterase (AChE) modulator. Gln-Leu inhibits AChE activity and increases AChE levels in the brain. Gln-Leu TFA ameliorates memory impairment.
For research use only. We do not sell to patients.
- CAS No.: 34027-65-1
- Formula: C11H21N3O4
- Molecular Weight:259.30
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
AChE |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:C57BL/6 (male, 7 weeks old)[1]
-
Dosage:10 mg/kg/day
-
Administration:p.o.; once daily; 14 days
-
Result:In scopolamine-exposed mice, the discrimination index in the novel object recognition test improved and step-through latency in the passive avoidance test increased relative to the scopolamine group.
Increased brain acetylcholine levels and decreased acetylcholinesterase activity relative to the scopolamine group.
Chemical Information
-
CAS No. 34027-65-1
-
Molecular Weight 259.30
-
Formula C11H21N3O4
-
Sequence
Gln-Leu
-
Sequence Shortening
QL
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Gln-Leu Related Classifications
HY-P12405 Related Classifications
Powered by Bioz