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GNF-8625

GNF-8625 is a broad-spectrum TRK inhibitor that can combine with Thalidomide to form a PROTAC degrader. The IC50 of GNF-8625 for inhibiting TRKA, TRKB, and TRKC are 0.8 nM, 22 nM, and 5.4 nM, respectively.

For research use only. We do not sell to patients.

  • CAS No.: 1196546-33-4
  • Formula: C31H30FN7O
  • Molecular Weight:535.61
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • GNF-8625 Chemical Structure
    GNF-8625 Chemical Structure
CAS No.: 1196546-33-4
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Use of MCE Products

All Trk Receptor Isoforms

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  • GNF-8625 Chemical Structure
    GNF-8625 Chemical Structure
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  • GNF-8625