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Harmaline analog

Harmaline analog (compound 3) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC₅₀ of 0.145 μM.

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CAS No.: 2411677-02-4
Formula: C₂₀H₁₉ClN₂O
Molecular Weight:338.83

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Harmaline analog Chemical Structure

CAS No.: 2411677-02-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Harmaline analog (compound 3) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC₅₀ of 0.145 μM^[1].

All COX Isoforms :

Chemical Information

CAS No. 2411677-02-4
Molecular Weight 338.83
Formula C₂₀H₁₉ClN₂O
SMILES

ClC1=CC=C(CN2C3=C(C4=C2C(C)=NCC4)C=C(OC)C=C3)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Uddin MJ, et al. Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors. ACS Med Chem Lett. 2020 Feb 14;11(10):1881-1885. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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References

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Harmaline analog

High-Throughput Bioactive Compound Library

All COX Isoforms