Insecticidal agent 34
Insecticidal agent 34 is an orally active insecticide. Insecticidal agent 34 inhibits voltage-gated sodium channel and blocks acetylcholine release. Insecticidal agent 34 induces ataxia, paralysis, curling, tremors/convulsions and progressive death in lepidopteran larvae, inhibits neural activity in the central nervous system, and blocks nerve firing in larval stretch receptor preparations. Insecticidal agent 34 can be used for insecticidal research.
For research use only. We do not sell to patients.
- CAS No.: 183992-66-7
- Formula: C29H28F6N2O5
- Molecular Weight:598.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Insecticidal agent 34 (Compound 4) potently inhibits veratridine-induced acetylcholine release from synaptosomes of the house cricket (Acheta domesticus), with a pIC50 of 6.56[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:late second instar larvae[1]
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Dosage:Diet incorporation
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Administration:continuous; 10 days
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Result:Exhibited slow-onset toxicity with an LC50 corresponding to a pLC50 of 5.7 after 10 days of diet exposure.
Achieved an IC50 for growth inhibition corresponding to a pI50 of 6.56 after 10 days of diet exposure.
Chemical Information
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CAS No. 183992-66-7
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Molecular Weight 598.53
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Formula C29H28F6N2O5
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SMILES
O=C(NC1=CC=C(CN2CCC(C(C3=CC=C(C=C3)OC(F)(F)F)(C4=CC=C(C=C4)OC(F)(F)F)O)CC2)C=C1)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Insecticidal agent 34 Related Classifications
HY-206897 Related Classifications
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- Insecticidal agent 34
- 183992-66-7
- Insecticidal agent34
- Insecticidal agent-34
- Insecticide
- Sodium Channel
- larval stretch receptor preparations
- cricket synaptosomes
- cockroaches
- central nervous system
- acetylcholine
- voltage-gated sodium channel
- flies
- lepidopteran larvae
- tobacco budworm larvae
- Acheta domesticus
- Inhibitor
- inhibitor
- inhibit