Huwentoxin I
Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 769973-37-7
- Formula: C161H246N48O44S6
- Molecular Weight:3750.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Calcium Channel Isoforms
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Biological Activity
Chemical Information
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CAS No. 769973-37-7
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Molecular Weight 3750.36
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Formula C161H246N48O44S6
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Synonyms
HWTX-I
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Sequence
Ala-Cys-Lys-Gly-Val-Phe-Asp-Ala-Cys-Thr-Pro-Gly-Lys-Asn-Glu-Cys-Cys-Pro-Asn-Arg-Val-Cys-Ser-Asp-Lys-His-Lys-Trp-Cys-Lys-Trp-Lys-Leu (Disulfide bridge: Cys2-Cys17; Cys9-Cys22; Cys16-Cys29)
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Sequence Shortening
ACKGVFDACTPGKNECCPNRVCSDKHKWCKWKL (Disulfide bridge: Cys2-Cys17; Cys9-Cys22; Cys16-Cys29)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)