Huwentoxin I
Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively.
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- CAS. Nr.: 769973-37-7
- Formel: C161H246N48O44S6
- Molecular Weight:3750.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 769973-37-7
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Molecular Weight 3750.36
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Formel C161H246N48O44S6
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Synonyms
HWTX-I
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Sequence
Ala-Cys-Lys-Gly-Val-Phe-Asp-Ala-Cys-Thr-Pro-Gly-Lys-Asn-Glu-Cys-Cys-Pro-Asn-Arg-Val-Cys-Ser-Asp-Lys-His-Lys-Trp-Cys-Lys-Trp-Lys-Leu (Disulfide bridge: Cys2-Cys17; Cys9-Cys22; Cys16-Cys29)
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Sequence Shortening
ACKGVFDACTPGKNECCPNRVCSDKHKWCKWKL (Disulfide bridge: Cys2-Cys17; Cys9-Cys22; Cys16-Cys29)
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)