QL-IX-55
QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1223002-54-7
- Formula: C24H14F4N4O
- Molecular Weight:450.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PC-3 | EC50 |
250 nM
Compound: 11
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Inhibition of PI3Kalpha in human PC3 cells expressing Akt1 S473D mutant assessed as phosphorylation of Akt Thr308 by immunoblotting
Inhibition of PI3Kalpha in human PC3 cells expressing Akt1 S473D mutant assessed as phosphorylation of Akt Thr308 by immunoblotting
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[PMID: 21322566] |
Chemical Information
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CAS No. 1223002-54-7
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Molecular Weight 450.39
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Formula C24H14F4N4O
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SMILES
NC1=NC=C(C2=CC=C(N=CC(C=C3)=C4N(C5=CC(C(F)(F)F)=C(F)C=C5)C3=O)C4=C2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
QL-IX-55 Related Classifications
HY-15281 Related Classifications
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