Idesin
Idesin is a compound found in the fruits of Idesia polycarpa. Idesin inhibits LPS (HY-D1056)-induced nitric oxide production with mild cytotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 20331-85-5
- Formula: C13H18O8
- Molecular Weight:302.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
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| 3T3-L1 | IC50 |
127.2 μM
Compound: 6
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Antiadipogenic activity in mouse 3T3L1 cells assessed as differentiation of preadipocytes to adipocytes after 8 days by spectrophotometry
Antiadipogenic activity in mouse 3T3L1 cells assessed as differentiation of preadipocytes to adipocytes after 8 days by spectrophotometry
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[PMID: 23628332] |
Idesin (Compound 4) (1-100 μM; 25 h) significantly inhibits LPS (HY-D1056)-induced NO production in BV2 microglial cells, with mild cytotoxicity at 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:BV2 mouse microglial cells (LPS-stimulated)
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Concentration:1 μM, 10 μM, 100 μM
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Incubation Time:25 h total (1 h pre-treatment + 24 h co-incubation with LPS)
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Result:Reduced nitrite levels to 7.0 ± 0.1 μM and resulted in 87.2 ± 4.2% cell viability at 1 μM.
Reduced nitrite levels to 5.5 ± 0.3 μM and resulted in 97.6 ± 6.3% cell viability at 10 μM.
Reduced nitrite levels to 4.9 ± 0.5 μM and resulted in 90.7 ± 6.8% cell viability at 100 μM.
Chemical Information
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CAS No. 20331-85-5
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Molecular Weight 302.28
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Formula C13H18O8
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SMILES
OCC(C=CC=C1O)=C1O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Idesin Related Classifications
HY-N18031 Related Classifications
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