IKKβ-IN-4
Based on 1 Customer Validation
IKKβ-IN-4 (compound 14) is an IkappaB kinase-β ( IKKβ ) inhibitor with IC50 value of 1.9 μM. IKKβ is a key enzyme in the NF-κB signaling pathway and is involved in the development of many diseases.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 4815-35-4
- Formula: C11H10N2OS
- Molecular Weight:218.27
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Immunology/Inflammation Compound Library
HY-L007
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Kinase Inhibitor Library
HY-L009
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NF-κB Signaling Compound Library
HY-L014
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Stem Cell Signaling Compound Library
HY-L017
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Anti-Aging Compound Library
HY-L034
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Differentiation Inducing Compound Library
HY-L038
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Anti-Liver Cancer Compound Library
HY-L101
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Anti-Prostate Cancer Compound Library
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Highly Selective Inhibitors Library
HY-L158
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Serine/Threonine Kinase Inhibitor Library
HY-L164
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
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Lactylation Compound Library
HY-L249
Biological Activity
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IKKβ 1.9 μM (IC50) |
Chemical Information
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CAS No. 4815-35-4
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Appearance Solid
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Molecular Weight 218.27
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Formula C11H10N2OS
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Color Light yellow to yellow
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SMILES
NC(SC(C1=CC=CC=C1)=C2)=C2C(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 116.67 mg/mL (534.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.5815 mL | 22.9074 mL | 45.8148 mL | 114.5370 mL |
| 5 mM | 0.9163 mL | 4.5815 mL | 9.1630 mL | 22.9074 mL | |
| 10 mM | 0.4581 mL | 2.2907 mL | 4.5815 mL | 11.4537 mL | |
| 15 mM | 0.3054 mL | 1.5272 mL | 3.0543 mL | 7.6358 mL | |
| 20 mM | 0.2291 mL | 1.1454 mL | 2.2907 mL | 5.7269 mL | |
| 25 mM | 0.1833 mL | 0.9163 mL | 1.8326 mL | 4.5815 mL | |
| 30 mM | 0.1527 mL | 0.7636 mL | 1.5272 mL | 3.8179 mL | |
| 40 mM | 0.1145 mL | 0.5727 mL | 1.1454 mL | 2.8634 mL | |
| 50 mM | 0.0916 mL | 0.4581 mL | 0.9163 mL | 2.2907 mL | |
| 60 mM | 0.0764 mL | 0.3818 mL | 0.7636 mL | 1.9090 mL | |
| 80 mM | 0.0573 mL | 0.2863 mL | 0.5727 mL | 1.4317 mL | |
| 100 mM | 0.0458 mL | 0.2291 mL | 0.4581 mL | 1.1454 mL |
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