IL-17 modulator 1 disodium
Based on 1 Customer Validation
IL-17 modulator 1 (disodium) is an orally active, highly efficacious IL-17 modulator extracted from patent WO 2020127685. IL-17 modulator 1 (disodium) can be used for the research of diseases including psoriasis, ankylosing spondylitis and psoriatic arthritis.
For research use only. We do not sell to patients.
- Purity: 98.38%
- CAS No.: 2446803-91-2
- Formula: C28H35N6Na2O6P
- Molecular Weight:628.57
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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IL-17 |
Chemical Information
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CAS No. 2446803-91-2
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Appearance Solid
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Molecular Weight 628.57
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Formula C28H35N6Na2O6P
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Color White to off-white
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SMILES
O=C(C1=CC=NN1C(C)C)N[C@H](C(NC2=CC=C(C3=C(N(N=C3C)COP(O[Na])(O[Na])=O)C)C=C2)=O)C(C4CC4)C5CC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20 mg/mL (31.82 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. WO 2020127685
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5909 mL | 7.9546 mL | 15.9091 mL | 39.7728 mL |
| 5 mM | 0.3182 mL | 1.5909 mL | 3.1818 mL | 7.9546 mL | |
| 10 mM | 0.1591 mL | 0.7955 mL | 1.5909 mL | 3.9773 mL | |
| 15 mM | 0.1061 mL | 0.5303 mL | 1.0606 mL | 2.6515 mL | |
| 20 mM | 0.0795 mL | 0.3977 mL | 0.7955 mL | 1.9886 mL | |
| 25 mM | 0.0636 mL | 0.3182 mL | 0.6364 mL | 1.5909 mL | |
| 30 mM | 0.0530 mL | 0.2652 mL | 0.5303 mL | 1.3258 mL |