1. GPCR/G Protein Neuronal Signaling
  2. mAChR
  3. Iperoxo

Iperoxo is a potent superagonist of muscarinic acetylcholine receptor (mAChR). [3H]Iperoxo can be used for direct probing activation-related conformational transitions of muscarinic receptors. Iperoxo is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Iperoxo Chemical Structure

Iperoxo Chemical Structure

CAS No. : 247079-84-1

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Solid + Solvent
10 mM * 1 mL in DMSO
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5 mg USD 135 In-stock
10 mg USD 250 In-stock
25 mg USD 525 In-stock
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Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Iperoxo

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Description

Iperoxo is a potent superagonist of muscarinic acetylcholine receptor (mAChR). [3H]Iperoxo can be used for direct probing activation-related conformational transitions of muscarinic receptors[1][2]. Iperoxo is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Molecular Weight

324.16

Formula

C10H17IN2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[N+](C)(C)CC#CCOC1=NOCC1.[I-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (192.81 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0849 mL 15.4245 mL 30.8490 mL
5 mM 0.6170 mL 3.0849 mL 6.1698 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0849 mL 15.4245 mL 30.8490 mL 77.1224 mL
5 mM 0.6170 mL 3.0849 mL 6.1698 mL 15.4245 mL
10 mM 0.3085 mL 1.5424 mL 3.0849 mL 7.7122 mL
15 mM 0.2057 mL 1.0283 mL 2.0566 mL 5.1415 mL
20 mM 0.1542 mL 0.7712 mL 1.5424 mL 3.8561 mL
25 mM 0.1234 mL 0.6170 mL 1.2340 mL 3.0849 mL
30 mM 0.1028 mL 0.5141 mL 1.0283 mL 2.5707 mL
40 mM 0.0771 mL 0.3856 mL 0.7712 mL 1.9281 mL
50 mM 0.0617 mL 0.3085 mL 0.6170 mL 1.5424 mL
60 mM 0.0514 mL 0.2571 mL 0.5141 mL 1.2854 mL
80 mM 0.0386 mL 0.1928 mL 0.3856 mL 0.9640 mL
100 mM 0.0308 mL 0.1542 mL 0.3085 mL 0.7712 mL
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Iperoxo Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Iperoxo
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HY-122743
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