Isofouquierol
Isofouquierol is a selective inhibitor targeting nitric oxide (NO) production with anti-inflammatory activity. Isofouquierol blocks NO overproduction by inhibiting the inducible nitric oxide synthase (iNOS)-related pathway. Isofouquierol can be used in the study of inflammation-related diseases (such as chronic inflammation, immune disorders).
For research use only. We do not sell to patients.
- CAS No.: 53822-99-4
- Formula: C30H52O3
- Molecular Weight:460.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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iNOS |
Isofouquierol (30 μM, 100 μM) inhibits NO production in lipopolysaccharide (LPS)-activated mouse peritoneal macrophages by 18.4% (30 μM) and 86.6% (100 μM), respectively [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 53822-99-4
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Molecular Weight 460.73
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Formula C30H52O3
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SMILES
C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]3([H])[C@@](C)(O)C/C=C/C(C)(O)C)C)([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC1)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Pakhathirathien C, et al. Dammarane triterpenes from the hypocotyls and fruits of Ceriops tagal. J Nat Prod. 2005 Dec;68(12):1787-9. [Content Brief]
[2]. Yoshikawa M, et al. Absolute stereostructures of olibanumols A, B, C, H, I, and J from olibanum, gum-resin of Boswellia carterii, and inhibitors of nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Chem Pharm Bull (Tokyo). 2009 Sep;57(9):957-64. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Isofouquierol Related Classifications
HY-N16735 Related Classifications
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