BIIL-260
Based on 1 publication(s) in Google Scholar
BIIL-260 is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with the Ki value of 1.7 nM.
For research use only. We do not sell to patients.
- CAS No.: 204974-93-6
- Formula: C30H30N2O3
- Molecular Weight:466.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) BIIL-260
MoreAll Leukotriene Receptor Isoforms
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Biological Activity
Ki: 1.7 nM (LTB4 receptor)[1]
BIIL-260 potently inhibits LTB4-induced intracellular Ca2+ release in human neutrophils with the IC50 value of 0.82 nM.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 204974-93-6
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Molecular Weight 466.57
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Formula C30H30N2O3
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SMILES
N=C(N)C1=CC=C(C=C1)OCC2=CC=CC(COC3=CC=C(C=C3)C(C4=CC=C(C=C4)O)(C)C)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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J Leukoc Biol
Caging giants: Characterizing the molecular mechanisms of neutrophil swarming against Candida albicans hyphae. [Abstract]2025 Jun 6:qiaf082. PMID: 40476443
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BIIL-260 Related Classifications
HY-114641 Related Classifications
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