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Cat. No.: HY-113793

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BPH-742

BPH-742 (compound 9) is a Geranylgeranyl diphosphate synthase inhibitor with IC₅₀ of 0.1 μM. BPH-742 has antitumor activity.

For research use only. We do not sell to patients.

CAS No.: 1059677-12-1
Formula: C₁₆H₃₇O₆P₃
Molecular Weight:418.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

BPH-742 Chemical Structure

CAS No.: 1059677-12-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BPH-742 (compound 9) is a Geranylgeranyl diphosphate synthase inhibitor with IC₅₀ of 0.1 μM. BPH-742 has antitumor activity^[1].

All Ras Isoforms :

Chemical Information

CAS No. 1059677-12-1
Molecular Weight 418.38
Formula C₁₆H₃₇O₆P₃
SMILES

O=[P]([O-])(O)C([P](O)(O)=O)C[P+](C)(C)CCCCCCCCCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. K-M et al. Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. J Med Chem. 2008 Sep 25;51(18):5594-607. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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References

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BPH-742

All Ras Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BPH-742 Related Classifications

HY-113793 Related Classifications