CYM50374
CYM50374 is a potent antagonist sphingosine-1-phosphate 4 (S1P4) antagonists, with the IC50 of 34 nM.
For research use only. We do not sell to patients.
- CAS No.: 1314212-81-1
- Formula: C19H19NO3S
- Molecular Weight:341.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U2OS | IC50 |
34 nM
Compound: 16, CYM50374
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Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TEV protease fusion protein and beta-lactamase reporter gene assessed as beta-lactamase expression by FRET a
Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TEV protease fusion protein and beta-lactamase reporter gene assessed as beta-lactamase expression by FRET a
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[PMID: 21570287] |
Chemical Information
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CAS No. 1314212-81-1
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Molecular Weight 341.42
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Formula C19H19NO3S
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SMILES
O=C(NC1=C(C=C(C=C1C)CO)C)C2=CC=C(O2)C3=C(C=CS3)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CYM50374 Related Classifications
HY-125046 Related Classifications
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