Eucatropine
Eucatropine is a potent muscarinic acetylcholine receptor (mAChR) inhibitor with an IC50 value of 0.583 μM. Eucatropine acts as an anticholinergic agent. Eucatropine produces behavioral effects via central cholinergic receptive sites in cats.
For research use only. We do not sell to patients.
- CAS No.: 100-91-4
- Formula: C17H25NO3
- Molecular Weight:291.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male and female (2-4 kg; intracerebroventricular cannula implantation)[1]
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Dosage:0.2 mg, 0.5 mg, 1.0 mg, 2.0 mg
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Administration:i.c.v.; single injection
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Result:Produced inconsistent emotional effects including miaowing, loud calling, loss of interest of the surroundings, rage, threat, attack, defense, fighting with paws, and flight; no restlessness, impelling locomotion, vacant staring, or apprehension.
Caused consistent mydriasis and tachypnea; inconsistent dyspnea, licking, vomiting, salivation, defecation, and micturition.
Induced consistent ataxia; no scratching, rigidity, weakness with adynamia, myoclonic jerks, or convulsions.
Showed no measurable impelling locomotion at any tested dose.
Caused very short-duration, non-dose-dependent aggressive fighting behavior with mean duration near 0 minutes across all tested doses.
Chemical Information
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CAS No. 100-91-4
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Molecular Weight 291.39
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Formula C17H25NO3
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SMILES
O=C(OC1CC(C)(C)N(C)C(C)C1)C(O)C2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Beleslin DB, et al. Comparative behavioral effects of anticholinergic agents in cats: psychomotor stimulation and aggression. Pharmacol Biochem Behav. 1986;24(3):581-586. [Content Brief]
[2]. Schmeller T, et, al. Binding of tropane alkaloids to nicotinic and muscarinic acetylcholine receptors. Pharmazie. 1995 Jul;50(7):493-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Eucatropine Related Classifications
HY-117284 Related Classifications
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