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RBFA - ribosome binding factor A Gene

Also Known as HsT169; C18orf22

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 79863

About RBFA

This gene has 5 transcripts (splice variants) and 143 orthologues. Ubiquitous expression in fat (RPKM 3.2), skin (RPKM 2.6) and 25 other tissues.

Summary

Predicted to be involved in rRNA processing. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

RBFA Products (2)

mRNA	Protein	Name
NM_001171967.2	NP_001165438.1	putative ribosome-binding factor A, mitochondrial isoform 2 precursor
NM_024805.3	NP_079081.2	putative ribosome-binding factor A, mitochondrial isoform 1 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25416956	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RBFA Protein Structure

RBFA

0
100
200
300
343 a.a.

Protein Preferred Names	Protein Names
putative ribosome-binding factor A, mitochondrial	ribosome binding factor A (putative)

RBFA Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	RBFA	Q8N0V3	CMTM6	Homo sapiens	Q9NX76	Y2H Array	32296183
Intra	RBFA	Q8N0V3	CMTM6	Homo sapiens	Q9NX76	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	CMTM6	Homo sapiens	Q9NX76	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	AGTRAP	Homo sapiens	Q6RW13-2	Y2H Array	32296183
Intra	RBFA	Q8N0V3	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	CMTM5	Homo sapiens	Q96DZ9-2	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	CMTM5	Homo sapiens	Q96DZ9-2	Y2H Array	32296183
Intra	RBFA	Q8N0V3	GPX8	Homo sapiens	Q8TED1	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	GPX8	Homo sapiens	Q8TED1	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	GPX8	Homo sapiens	Q8TED1	Y2H Array	32296183
Intra	RBFA	Q8N0V3	SMIM5	Homo sapiens	Q71RC9	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	SMIM5	Homo sapiens	Q71RC9	Y2H Array	32296183
Intra	RBFA	Q8N0V3	HIGD1C	Homo sapiens	A8MV81	Y2H Array	32296183
Intra	RBFA	Q8N0V3	HIGD1C	Homo sapiens	A8MV81	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	GPR152	Homo sapiens	Q8TDT2	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
Intra	RBFA	Q8N0V3	RHEX	Homo sapiens	Q6ZWK4	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	RHEX	Homo sapiens	Q6ZWK4	Y2H Array	32296183
Intra	RBFA	Q8N0V3	CMTM5	Homo sapiens	Q96DZ9	Y2H Array	25416956
Intra	RBFA	Q8N0V3	YIF1A	Homo sapiens	O95070	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	YIF1A	Homo sapiens	O95070	Y2H Array	32296183
Intra	RBFA	Q8N0V3	SYPL1	Homo sapiens	Q16563	Y2H Array	32296183
Intra	RBFA	Q8N0V3	SYPL1	Homo sapiens	Q16563	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	ABHD5	Homo sapiens	Q8WTS1	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	ABHD5	Homo sapiens	Q8WTS1	Y2H Array	32296183
Intra	RBFA	Q8N0V3	ABHD5	Homo sapiens	Q8WTS1	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	ERLIN1	Homo sapiens	O75477	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	ERLIN1	Homo sapiens	O75477	Y2H Array	32296183
Intra	RBFA	Q8N0V3	CAV3	Homo sapiens	P56539	Y2H Array	32296183
Intra	RBFA	Q8N0V3	CAV3	Homo sapiens	P56539	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	FKBP7	Homo sapiens	Q9Y680	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	FKBP7	Homo sapiens	Q9Y680	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	FKBP7	Homo sapiens	Q9Y680	Y2H Array	32296183
Intra	RBFA	Q8N0V3	PEX12	Homo sapiens	O00623	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	PEX12	Homo sapiens	O00623	Y2H Array	32296183
Intra	RBFA	Q8N0V3	MDK	Homo sapiens	P21741	Y2H Array	32296183
Intra	RBFA	Q8N0V3	MDK	Homo sapiens	P21741	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	FATE1	Homo sapiens	Q969F0	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	FATE1	Homo sapiens	Q969F0	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	FATE1	Homo sapiens	Q969F0	Y2H Array	32296183
Intra	RBFA	Q8N0V3	LEPROTL1	Homo sapiens	O95214	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	LEPROTL1	Homo sapiens	O95214	Y2H Array	32296183
Intra	RBFA	Q8N0V3	DERL2	Homo sapiens	Q9GZP9	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	DERL2	Homo sapiens	Q9GZP9	Y2H Array	32296183
Intra	RBFA	Q8N0V3	DERL2	Homo sapiens	Q9GZP9	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	CACFD1	Homo sapiens	Q9UGQ2	Y2H Array	32296183
Intra	RBFA	Q8N0V3	CACFD1	Homo sapiens	Q9UGQ2	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	CACFD1	Homo sapiens	Q9UGQ2	Validated Y2H	32296183
Intra	RBFA	Q8N0V3	SYP	Homo sapiens	P08247	Y2H Prey Pooling	32296183
Intra	RBFA	Q8N0V3	SYP	Homo sapiens	P08247	Y2H Array	32296183
Intra	RBFA	Q8N0V3	ANK1	Homo sapiens	P16157-17	Y2H Array	32296183
Intra	RBFA	Q8N0V3	ANK1	Homo sapiens	P16157-17	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Raynaud-Claes Syndrome	Mrx49 MRXSRC Mental Retardation, X-Linked 49 Mrx15 Clcn4-Related X-Linked Intellectual Disability Syndrome Mental Retardation, X-Linked 15 X-Linked Mental Retardation 15 X-Linked Mental Retardation 49 Mental Retardation, X-Linked-49

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11723	RBFA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RBFA	VGNC	VGNC:49568
Mus musculus	RBFA	MGD	MGI:1915981
Rattus norvegicus	RBFA	RGD	RGD:1311910
Macaca mulatta	RBFA	VGNC	VGNC:76542
Others	RBFA	NCBI