NC1153
NC1153 is a Mannich base with the activity to block IL-2-induced JAK3 activation and its downstream substrate STAT5a/b. NC1153 effectively prolongs the survival of kidney transplants in MHC/non-MHC mismatched rats. NC1153 promotes long-term graft survival and includes multiple toxicity protection for recipients. NC1153 combined with cyclosporine A (CsA) can synergistically prolong graft survival without producing nephrotoxicity, myelotoxicity or lipotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 150661-91-9
- Formula: C18H38Cl2N2O
- Molecular Weight:369.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 150661-91-9
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Molecular Weight 369.41
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Formula C18H38Cl2N2O
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SMILES
O=C1C(CN(C)C)CCCCCCCCCC1CN(C)C.Cl.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NC1153 Related Classifications
HY-115464 Related Classifications
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