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Cat. No.: HY-120053

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SC-53606

SC-53606 is a potent and selective 5-HT₄ receptor antagonist, with a pA2 value of 8.13. SC-53606 acts as an antagonist of 5-HT₄ receptor-mediated relaxation of Carbachol (HY-B1208)-induced contractions.

For research use only. We do not sell to patients.

CAS No.: 151898-33-8
Formula: C₁₆H₁₉ClN₄O
Molecular Weight:318.80

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

SC-53606 Chemical Structure

CAS No.: 151898-33-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]^[2]

5-HT₄ Receptor

All 5-HT Receptor Isoforms :

Chemical Information

CAS No. 151898-33-8
Molecular Weight 318.80
Formula C₁₆H₁₉ClN₄O
SMILES

O=C(NC[C@H]1[C@@]2(CCCN2CC1)[H])C3=CC(Cl)=CN4C3=NC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang DC, et al. SC-53606, a potent and selective antagonist of 5-hydroxytryptamine4 receptors in isolated rat esophageal tunica muscularis mucosae. J Pharmacol Exp Ther. 1993 Sep;266(3):1339-47. [Content Brief]

[2]. Becker D P, et al. Design and synthesis of agonists and antagonists of the serotonin 5-HT4 receptor subtype. Pharmacochemistry Library. Elsevier, 1996, 24: 99-120.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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