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Cat. No.: HY-124919

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JJO-1

JJO-1 is an AMPK activator with an EC₅₀ of 1.8 μM. JJO-1 can be used in the study of obesity and type 2 diabetes.

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CAS No.: 16722-44-4
Formule: C₁₉H₁₃N₃
Masse moléculaire:283.33

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

JJO-1 Chemical Structure

CAS No.: 16722-44-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

JJO-1 is an AMPK activator with an EC₅₀ of 1.8 μM. JJO-1 can be used in the study of obesity and type 2 diabetes^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
COS-7	EC₅₀	1.8 μM Compound: 29	Activation of human recombinant AMPK GST-tagged alpha1/Myc-tagged beta1/HA-tagged gamma1 expressed in African green monkey COS7 cells assessed as increase in SAMS peptide phosphorylation measured after 10 mins in presence of [gamma33P]ATP by scintillation Activation of human recombinant AMPK GST-tagged alpha1/Myc-tagged beta1/HA-tagged gamma1 expressed in African green monkey COS7 cells assessed as increase in SAMS peptide phosphorylation measured after 10 mins in presence of [gamma33P]ATP by scintillation	[PMID: 27727125]

Chemical Information

CAS No. 16722-44-4
Masse moléculaire 283.33
Formule C₁₉H₁₃N₃
SMILES

C1(/C=N/C2=CN=C3C=CC=CC3=C2)=CC=C4C=CC=CC4=N1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Scott JW, Oakhill JS, Ling NX, Langendorf CG, Foitzik RC, Kemp BE, Issinger OG. ATP sensitive bi-quinoline activator of the AMP-activated protein kinase. Biochem Biophys Res Commun. 2014 Jan 10;443(2):435-40. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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JJO-1

Voir tous les produits spécifiques à Isoform AMPK

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

JJO-1 Related Classifications

HY-124919 Related Classifications