LHC-165
Based on 1 Customer Validation
LHC-165 is a TLR7 agonist. LHC-165 has potential to used in study of solid tumors.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1258595-14-0
- Formula: C29H32F2N3O7P
- Molecular Weight:603.55
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
|
TLR7 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1258595-14-0
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Appearance Solid
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Molecular Weight 603.55
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Formula C29H32F2N3O7P
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Color Light yellow to yellow
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SMILES
NC1=C2C(C=C(CCC3=CC=C(OCCOCCC(F)(F)P(O)(O)=O)C=C3C)C=N2)=C4C(C=C(CCC(O)=O)C=C4)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
1M NaOH : 50 mg/mL (82.84 mM; ultrasonic and adjust pH to 12 with NaOH)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 1M NaOH | 1 mM | 1.6569 mL | 8.2843 mL | 16.5686 mL | 41.4216 mL |
| 5 mM | 0.3314 mL | 1.6569 mL | 3.3137 mL | 8.2843 mL | |
| 10 mM | 0.1657 mL | 0.8284 mL | 1.6569 mL | 4.1422 mL | |
| 15 mM | 0.1105 mL | 0.5523 mL | 1.1046 mL | 2.7614 mL | |
| 20 mM | 0.0828 mL | 0.4142 mL | 0.8284 mL | 2.0711 mL | |
| 25 mM | 0.0663 mL | 0.3314 mL | 0.6627 mL | 1.6569 mL | |
| 30 mM | 0.0552 mL | 0.2761 mL | 0.5523 mL | 1.3807 mL | |
| 40 mM | 0.0414 mL | 0.2071 mL | 0.4142 mL | 1.0355 mL | |
| 50 mM | 0.0331 mL | 0.1657 mL | 0.3314 mL | 0.8284 mL | |
| 60 mM | 0.0276 mL | 0.1381 mL | 0.2761 mL | 0.6904 mL | |
| 80 mM | 0.0207 mL | 0.1036 mL | 0.2071 mL | 0.5178 mL |