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LSN3074753

LSN3074753, an analog of LY3009120 (HY-12558), is a pan-RAF and Raf dimer inhibitor. LSN3074753 demonstrates activity against tumor cells with MAPK pathway activation driven by BRAF monomer or RAF dimers including BRAF- or KRAS-mutant colorectal cancer. LSN3074753 combined with Cetuximab (HY-P9905) shows additive and synergistic effects for colorectal cancer PDX models, particularly those with KRAS or BRAF mutation.

For research use only. We do not sell to patients.

  • CAS No.: 1455031-68-1
  • Formula: C24H30FN5O2
  • Molecular Weight:439.53
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • LSN3074753 Chemical Structure
    LSN3074753 Chemical Structure
CAS No.: 1455031-68-1
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All Raf Isoforms

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100 mg

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  • LSN3074753 Chemical Structure
    LSN3074753 Chemical Structure
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  • LSN3074753