1,2-Hexanediol
Based on 1 Customer Validation
1,2-Hexanediol (Hexane-1,2-diol) is a broad-spectrum antibacterial agent. 1,2-Hexanediol exhibits bactericidal activity against Gram-positive and Gram-negative bacteria, as well as antifungal activity against fungal organisms. 1,2-Hexanediol disrupts the cytoplasmic membrane potential of bacteria. 1,2-Hexanediol can be used in research on bacterial and fungal infections, as well as cosmetic preservation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 6920-22-5
- 分子式: C6H14O2
- 分子量:118.18
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保管条件:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
1,2-hexanediol (195-100000 ppm; 24-72 h) inhibits the growth of Escherichia coli NCTC 12923, Staphylococcus aureus NCTC 10788, Candida albicans NCPF 3179, and Aspergillus brasiliensis NCPF 2275, with MIC values of 12500, 25000, 12500, and 6250 ppm, respectively[1].
1,2-hexanediol (0-25000 ppm; 24-48 h) exerts synergistic inhibitory effects with Nicotinamide (HY-B0150) against Candida albicans NCPF 3179 and Aspergillus brasiliensis NCPF 2275, with FICI values of 0.375 and 0.3125, respectively; it exerts synergistic inhibitory effects with sodium cocoyl methyl taurate and sodium cocoyl alaninate against Escherichia coli NCTC 12923, with an FICI value of 0.375 for each combination; it also exerts a synergistic inhibitory effect with sodium C14-16 olefin sulfonate against Aspergillus brasiliensis NCPF 2275, with an FICI value of 0.375[1].
1,2-Hexanediol disrupts the cytoplasmic membrane potential of B. cereus ATCC 21772[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 6920-22-5
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性状 Liquid (Density: 0.951 g/cm3)
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分子量 118.18
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分子式 C6H14O2
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Color Colorless to light yellow
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SMILES
OCC(O)CCCC
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別名
Hexane-1,2-diol
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
純度とドキュメンテーション
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データシート (264 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Gim H, et al. Synergistic/antagonistic antimicrobial effects of cosmetic ingredients in combination with 1,2-hexanediol. J Microorg Control. 2024;29(4):133-142. [Content Brief]
[2]. Yogiara, et al. Food-grade antimicrobials potentiate the antibacterial activity of 1,2-hexanediol. Lett Appl Microbiol. 2015;60(5):431-439. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
1,2-Hexanediol 関連分類
HY-W012880 関連分類
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- 1,2-Hexanediol
- 6920-22-5
- Hexane-1,2-diol
- Environmental Pollutants
- Fungal
- Bacterial
- bacterial cytoplasmic membrane potential
- niacinamide
- Staphylococcus aureus NCTC 10788
- Aspergillus brasiliensis NCPF 2275
- fungi
- Escherichia coli NCTC 12923
- Gram-positive bacteria
- Gram-negative bacteria
- Candida albicans NCPF 3179
- Bacillus cereus
- ntimicrobial agent
- Inhibitor
- inhibitor
- inhibit