Alizapride
Based on 1 publication(s) in Google Scholar
Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 59338-93-1
- 分子式: C16H21N5O2
- 分子量:315.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Alizapride
MoreDopamine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
Dopamine 2 receptor
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Duncan–Hartley guinea pigs[2]
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Dosage:2.5, 5, 10, 25 μg/kg
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Administration:Alizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days)
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Result:Reduced the clearance of IgG-sensitized RBCs.
化学情報
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CAS 番号 59338-93-1
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分子量 315.37
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分子式 C16H21N5O2
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SMILES
O=C(C1=C(OC)C=C(NN=N2)C2=C1)NCC3N(CC=C)CCC3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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bioRxiv
A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG. [Abstract]2026 Apr 18:2026.04.17.719256. PMID: 42039650
純度とドキュメンテーション
参考文献
[1]. P L Warzee, et al. Manometric study of the activity of alizapride on the motor function of the human sphincter of Oddi. J Clin Pharm Ther. 1988 Aug;13(4):281-4. [Content Brief]
[2]. Gomez, et al. Macrophage Fcgamma receptors expression is altered by treatment with dopaminergic drugs. Clinical immunology (Orlando, Fla.) vol. 90,3 (1999): 375-87. [Content Brief]
[3]. Seng, et al. Anti-emetic effect of high-dose metoclopramide vs alizapride--a randomised crossover study. British journal of clinical pharmacology vol. 38,3 (1994): 282-4. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Alizapride 関連分類
HY-A0125 関連分類
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