country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-111653

Copy Link Print Information

CycLuc1

3 Cited Publications

カスタマーレビュー

Based on 3 publication(s) in Google Scholar

CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 99.72%
CAS 番号: 1247879-16-8
分子式: C₁₃H₁₁N₃O₂S₂
分子量:305.38

保管条件:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

CycLuc1 構造式

CAS 番号: 1247879-16-8

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

IC₅₀ & Target

Luciferase^[1]

体内実験

CycLuc1 (0.05-5 mM, intraperitoneally injected) can improve bioluminescence imaging (BLI) of the existing luciferase reporter protein in mice and achieve brain imaging that D-luciferin cannot achieve^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mouse xenograft tumor models^[2]
Dosage:

0.05, 0.5, 1, 5 mM, 100 μL
Administration:

i.p.
Result:

Yielded a >10-fold higher bioluminescent signal than could be obtained from D-luciferin injection at equivalent doses.

化学情報

CAS 番号 1247879-16-8
性状 Solid
分子量 305.38
分子式 C₁₃H₁₁N₃O₂S₂
Color Yellow to brown
SMILES

O=C([C@@H]1N=C(C2=NC3=CC4=C(NCC4)C=C3S2)SC1)O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Publications (3)

All Bio/Physico-chemical AssayIn Vivo Imaging

Sort by:

Journal Impact Factor

Sci Rep

Real-time bioluminescence imaging of mycobacteria with Akaluc: a novel method for monitoring drug efficacy. [Abstract]

2026 May 15;16(1):15193. PMID: 42151204
Microbiol Spectr

Near-infrared in vivo imaging system for dynamic visualization of lung-colonizing bacteria in mouse pneumonia. [Abstract]

2024 Nov 5;12(11):e0082824. PMID: 39287455

CycLuc1 purchased from MedChemExpress. Usage Cited in: Microbiol Spectr. 2024 Nov 5;12(11):e0082824. [Abstract]

The luminescence signals of the ATCC 17978-Luc strain with CycLuc1 (10 μM) was 9.0 × 10⁵ RLU.
bioRxiv

2023 Apr 29.

CycLuc1 purchased from MedChemExpress. Usage Cited in: bioRxiv. 2023 Apr 29.

CycLuc1 (5 mM, 10 μL/g) injection improved signal detection in the head in CAG-LSL-oFluc mice.

CycLuc1 purchased from MedChemExpress. Usage Cited in: bioRxiv. 2023 Apr 29.

RLU of the tissue extracts of oFluc from C57BL/6 mice supplemented with CycLuc1 (1 mM).

溶剤 & 溶解度

体外:

DMSO : 50 mg/mL (163.73 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

3.2746 mL

16.3730 mL

32.7461 mL

5 mM

0.6549 mL

3.2746 mL

6.5492 mL

10 mM

0.3275 mL

1.6373 mL

3.2746 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (273 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Shiv K, et al. Abstract 4112: Synthetic luciferin, CycLuc1, improves bioluminescence imaging for intracranial glioblastoma xenografts. 10.1158/1538-7445.AM2018-4112

[2]. Evans MS, et al. A synthetic luciferin improves bioluminescence imaging in live mice. Nat Methods. 2014 Apr;11(4):393-5. doi: 10.1038/nmeth.2839. Epub 2014 Feb 9. Erratum in: Nat Methods. 2014 Apr;11(4):395. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	3.2746 mL	16.3730 mL	32.7461 mL	81.8652 mL
	5 mM	0.6549 mL	3.2746 mL	6.5492 mL	16.3730 mL
	10 mM	0.3275 mL	1.6373 mL	3.2746 mL	8.1865 mL
	15 mM	0.2183 mL	1.0915 mL	2.1831 mL	5.4577 mL
	20 mM	0.1637 mL	0.8187 mL	1.6373 mL	4.0933 mL
	25 mM	0.1310 mL	0.6549 mL	1.3098 mL	3.2746 mL
	30 mM	0.1092 mL	0.5458 mL	1.0915 mL	2.7288 mL
	40 mM	0.0819 mL	0.4093 mL	0.8187 mL	2.0466 mL
	50 mM	0.0655 mL	0.3275 mL	0.6549 mL	1.6373 mL
	60 mM	0.0546 mL	0.2729 mL	0.5458 mL	1.3644 mL
	80 mM	0.0409 mL	0.2047 mL	0.4093 mL	1.0233 mL
	100 mM	0.0327 mL	0.1637 mL	0.3275 mL	0.8187 mL

Bioz

Keywords

CycLuc1

3 Cited Publications

100 mg お問い合わせ

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ

Amount: USD 0.00

1/16
1/16

CycLuc1 purchased from MedChemExpress. Usage Cited in: Microbiol Spectr. 2024 Nov 5;12(11):e0082824. [Abstract]

Customer Validation
The luminescence signals of the ATCC 17978-Luc strain with CycLuc1 (10 μM) was 9.0 × 10⁵ RLU.
1/16

CycLuc1 purchased from MedChemExpress. Usage Cited in: bioRxiv. 2023 Apr 29.

Customer Validation
CycLuc1 (5 mM, 10 μL/g) injection improved signal detection in the head in CAG-LSL-oFluc mice.
1/16

CycLuc1 purchased from MedChemExpress. Usage Cited in: bioRxiv. 2023 Apr 29.

Customer Validation
RLU of the tissue extracts of oFluc from C57BL/6 mice supplemented with CycLuc1 (1 mM).

製品名:
製品番号:
数量:
日本の代理先をお選びください:

製品名:
CAS 番号:
生物種:
純度:
数量:

CycLuc1

D-Luciferin

SBE-β-CD

D-Luciferin potassium

Forskolin

Capivasertib

Belnacasan

Z-VAD-FMK

Vorinostat

Venetoclax

Laduviglusib

Niraparib

Doxycycline hyclate

MedChemExpress（MCE）の使用を引用している文献 CycLuc1

生物活性

化学情報

Publications (3)

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

Bioz

CycLuc1

D-Luciferin

SBE-β-CD

D-Luciferin potassium

Forskolin

Capivasertib

Belnacasan

Z-VAD-FMK

Vorinostat

Venetoclax

Laduviglusib

Niraparib

Doxycycline hyclate

MedChemExpress（MCE）の使用を引用している文献 CycLuc1

生物活性

化学情報

Publications (3)

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

CycLuc1 関連分類

HY-111653 関連分類

Bioz