GOAT-IN-1
Based on 1 Customer Validation
GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.38%
- CAS 番号: 1452473-54-9
- 分子式: C18H13ClF3NO3S
- 分子量:415.81
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
The inhibitory activity of GOAT-IN-1 (Example 16) for human GOAT is 101% with the concentration of 10 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1452473-54-9
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性状 Solid
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分子量 415.81
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分子式 C18H13ClF3NO3S
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Color White to off-white
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SMILES
CC1=NC(C(F)(F)F)=CC=C1COC2=CC(SC=C3CC(O)=O)=C3C(Cl)=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 150 mg/mL (360.74 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4049 mL | 12.0247 mL | 24.0494 mL | 60.1236 mL |
| 5 mM | 0.4810 mL | 2.4049 mL | 4.8099 mL | 12.0247 mL | |
| 10 mM | 0.2405 mL | 1.2025 mL | 2.4049 mL | 6.0124 mL | |
| 15 mM | 0.1603 mL | 0.8016 mL | 1.6033 mL | 4.0082 mL | |
| 20 mM | 0.1202 mL | 0.6012 mL | 1.2025 mL | 3.0062 mL | |
| 25 mM | 0.0962 mL | 0.4810 mL | 0.9620 mL | 2.4049 mL | |
| 30 mM | 0.0802 mL | 0.4008 mL | 0.8016 mL | 2.0041 mL | |
| 40 mM | 0.0601 mL | 0.3006 mL | 0.6012 mL | 1.5031 mL | |
| 50 mM | 0.0481 mL | 0.2405 mL | 0.4810 mL | 1.2025 mL | |
| 60 mM | 0.0401 mL | 0.2004 mL | 0.4008 mL | 1.0021 mL | |
| 80 mM | 0.0301 mL | 0.1503 mL | 0.3006 mL | 0.7515 mL | |
| 100 mM | 0.0240 mL | 0.1202 mL | 0.2405 mL | 0.6012 mL |