K-Ras G12C-IN-2
K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1629267-75-9
- 分子式: C21H27ClN4O3
- 分子量:418.92
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
製品説明
IC50 & Target
[1]|
KRas G12C |
体外実験
化学情報
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CAS 番号 1629267-75-9
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性状 Solid
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分子量 418.92
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分子式 C21H27ClN4O3
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Color White to off-white
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SMILES
ClC1=C(C2CC2)C=C(NCC(N3CCN(C4CN(C(C=C)=O)C4)CC3)=O)C(O)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : ≥ 22 mg/mL (52.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3871 mL | 11.9355 mL | 23.8709 mL | 59.6773 mL |
| 5 mM | 0.4774 mL | 2.3871 mL | 4.7742 mL | 11.9355 mL | |
| 10 mM | 0.2387 mL | 1.1935 mL | 2.3871 mL | 5.9677 mL | |
| 15 mM | 0.1591 mL | 0.7957 mL | 1.5914 mL | 3.9785 mL | |
| 20 mM | 0.1194 mL | 0.5968 mL | 1.1935 mL | 2.9839 mL | |
| 25 mM | 0.0955 mL | 0.4774 mL | 0.9548 mL | 2.3871 mL | |
| 30 mM | 0.0796 mL | 0.3978 mL | 0.7957 mL | 1.9892 mL | |
| 40 mM | 0.0597 mL | 0.2984 mL | 0.5968 mL | 1.4919 mL | |
| 50 mM | 0.0477 mL | 0.2387 mL | 0.4774 mL | 1.1935 mL |
K-Ras G12C-IN-2 関連分類
HY-18605 関連分類
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