K-Ras G12C-IN-3
Based on 1 Customer Validation
K-Ras G12C-IN-3 (Compound VI-5) is an irreversible small molecule inhibitor of mutant K-Ras G12C. K-Ras G12C-IN-3 can be used in the research of cancers.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.94%
- CAS 番号: 1629268-19-4
- 分子式: C21H19Cl3N2O3
- 分子量:453.75
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
生物活性
化学情報
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CAS 番号 1629268-19-4
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性状 Solid
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分子量 453.75
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分子式 C21H19Cl3N2O3
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Color White to off-white
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SMILES
ClC(C=C(OC)C(C(N1CCN(C(C=C)=O)CC1)=O)=C2)=C2C3=CC(Cl)=CC=C3Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
DMSO : ≥ 30 mg/mL (66.12 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2039 mL | 11.0193 mL | 22.0386 mL | 55.0964 mL |
| 5 mM | 0.4408 mL | 2.2039 mL | 4.4077 mL | 11.0193 mL | |
| 10 mM | 0.2204 mL | 1.1019 mL | 2.2039 mL | 5.5096 mL | |
| 15 mM | 0.1469 mL | 0.7346 mL | 1.4692 mL | 3.6731 mL | |
| 20 mM | 0.1102 mL | 0.5510 mL | 1.1019 mL | 2.7548 mL | |
| 25 mM | 0.0882 mL | 0.4408 mL | 0.8815 mL | 2.2039 mL | |
| 30 mM | 0.0735 mL | 0.3673 mL | 0.7346 mL | 1.8365 mL | |
| 40 mM | 0.0551 mL | 0.2755 mL | 0.5510 mL | 1.3774 mL | |
| 50 mM | 0.0441 mL | 0.2204 mL | 0.4408 mL | 1.1019 mL | |
| 60 mM | 0.0367 mL | 0.1837 mL | 0.3673 mL | 0.9183 mL |