LHC-165
Based on 1 Customer Validation
LHC-165 is a TLR7 agonist. LHC-165 has potential to used in study of solid tumors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 1258595-14-0
- 分子式: C29H32F2N3O7P
- 分子量:603.55
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保管条件:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
生物活性
|
TLR7 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 1258595-14-0
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性状 Solid
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分子量 603.55
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分子式 C29H32F2N3O7P
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Color Light yellow to yellow
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SMILES
NC1=C2C(C=C(CCC3=CC=C(OCCOCCC(F)(F)P(O)(O)=O)C=C3C)C=N2)=C4C(C=C(CCC(O)=O)C=C4)=N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
1M NaOH : 50 mg/mL (82.84 mM; ultrasonic and adjust pH to 12 with NaOH)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 1M NaOH | 1 mM | 1.6569 mL | 8.2843 mL | 16.5686 mL | 41.4216 mL |
| 5 mM | 0.3314 mL | 1.6569 mL | 3.3137 mL | 8.2843 mL | |
| 10 mM | 0.1657 mL | 0.8284 mL | 1.6569 mL | 4.1422 mL | |
| 15 mM | 0.1105 mL | 0.5523 mL | 1.1046 mL | 2.7614 mL | |
| 20 mM | 0.0828 mL | 0.4142 mL | 0.8284 mL | 2.0711 mL | |
| 25 mM | 0.0663 mL | 0.3314 mL | 0.6627 mL | 1.6569 mL | |
| 30 mM | 0.0552 mL | 0.2761 mL | 0.5523 mL | 1.3807 mL | |
| 40 mM | 0.0414 mL | 0.2071 mL | 0.4142 mL | 1.0355 mL | |
| 50 mM | 0.0331 mL | 0.1657 mL | 0.3314 mL | 0.8284 mL | |
| 60 mM | 0.0276 mL | 0.1381 mL | 0.2761 mL | 0.6904 mL | |
| 80 mM | 0.0207 mL | 0.1036 mL | 0.2071 mL | 0.5178 mL |