AB13-08
AB13-08 is a selective dopamine receptor agonist with a Ki value of 53.9 nM for human D3R. AB13-08 is applicable to the research of neurological disorders such as Parkinson's disease and schizophrenia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C24H31N7O2
- 分子量:449.55
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Dopamine Receptor アイソフォーム固有の製品をすべて表示
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生物活性
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Human D3 Receptor 53.9 nM (Ki) |
Human D2 Receptor 2690 nM (Ki) |
AB13-08 (compound 4b) (90 min) binds to human D3 receptors expressed in HEK293 cells with a Ki value of 53.9 nM, and exhibits 49.9-fold binding selectivity over human D2 receptors (with a Ki value of 2690 nM)[1].
AB13-08 acts as a full agonist on human D3 receptors expressed in HEK293T cells, with a potency of 1.10 nM, and exhibits over 2800-fold potency selectivity over human D2 receptors[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 449.55
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分子式 C24H31N7O2
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SMILES
NC1=NC=C(C=C1)[C@H]2CN([C@H](CO2)C)CCCCNC(C3=CC(C)=CC=C3N4N=CC=N4)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AB13-08 関連分類
HY-184588 関連分類
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