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Adebrelimab

(別名: SHR-1316)
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Based on 1 Customer Validation

Adebrelimab (SHR-1316) is a humanized IgG4 monoclonal PD-L1 (PD-1/PD-L1) antibody. Adebrelimab has promising antitumor activity in solid tumors including extensive-stage small-cell lung cancer (SCLC).

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  • 純度: 99.06%
  • CAS 番号: 2247114-85-6
  • 分子量:145.56 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Adebrelimab
  • Experimental Validation Results for Adebrelimab
  • Experimental Validation Results for Adebrelimab
  • Adebrelimab Chemical Structure
    Adebrelimab 構造式
CAS 番号: 2247114-85-6
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometric analysis of 1.5X106 MDA-MB-231 cells labeling Adebrelimab (HY-P99422, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Immobilized HuPD-L1-hFc can bind Adebrelimab. The EC50 for this effect is 4.213 ng/mL.

  • Adebrelimab Chemical Structure
    1/16
  • Adebrelimab
  • Flow cytometric analysis of 1.5X106 MDA-MB-231 cells labeling Adebrelimab (HY-P99422, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Immobilized HuPD-L1-hFc can bind Adebrelimab. The EC50 for this effect is 4.213 ng/mL.